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Anti-RBPJK Antibody (5Y131) is a Rabbit antibody targeting RBPJK. Anti-RBPJK Antibody (5Y131) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
| Description | Anti-RBPJK Antibody (5Y131) is a Rabbit antibody targeting RBPJK. Anti-RBPJK Antibody (5Y131) can be used in WB. |
| Synonyms | SUH_HUMAN, SUH, Renal carcinoma antigen NY-REN-30, Recombining binding protein suppressor of hairless, recombination signal binding protein for immunoglobulin kappa J region, RBPSUH, RBP-JK, RBPJK, RBP-J kappa, RBP-J, Rbpj, RBP JK, RBP J kappa, RBP J, NY REN 30 antigen, KBF2, J kappa-recombination signal-binding protein, J kappa recombination signal binding protein, IGKJRB1, IGKJRB, csl, CBF-1, CBF1, CBF 1, AOS3, AI843960 |
| Ig Type | IgG |
| Clone | 5Y131 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of RBPJK on human colon tissue lysates using anti-RBPJK antibody at 1/500 dilution. ![]() |
| Application | |
| Recommended Dose | WB: 1:1000-5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Recombination signal binding protein Jκ (RBP-Jκ), also designated KBF2 or CBF1, is the mammalian homolog of the Drosophila suppressor of hairless (Su(H)), a protein involved in the development of the peripheral nervous system. RBP-Jκ is ubiquitously expressed in mammalian tissues and is involved in the regulation of gene expression. RBP-Jκ has been shown to directly interact with the intercellular domain of the cell surface receptor Notch 1. Proteolytically cleaved Notch 1 translocates to the nucleus, where it binds DNA-bound RBP-Jκ and activates transcription of target genes. These genes include NFκB p52 and the Epstein-Barr virus (EBV) protein EBNA-2, both of which contain RBP-Jκ-binding sequences within their promoter regions. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 55 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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