Oncostatin M/OSM Protein, Human, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-00146 Copy Product Info

Oncostatin M/OSM Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.1 kDa and the accession number is P13725.

Oncostatin M/OSM Protein, Human, Recombinant (His & Avi), Biotinylated

Catalog No. TMPK-00146

Copy Product Info

Oncostatin M/OSM Protein, Human, Recombinant (His & Avi), Biotinylated

Pack Size	Price	USA Stock	Global Stock
5 μg	$91	7-10 days	7-10 days
10 μg	$148	7-10 days	7-10 days
20 μg	$245	7-10 days	7-10 days
50 μg	$483	7-10 days	7-10 days
100 μg	$813	7-10 days	7-10 days
200 μg	$1,470	7-10 days	7-10 days
500 μg	$3,250	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Product Information

Biological Activity	Human LIF R, His Tag immobilized on CM5 Chip can bind Biotinylated Human Oncostatin M, His Tag with an affinity constant of 0.94 μM as determined in SPR assay.
Description	Oncostatin M/OSM Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.1 kDa and the accession number is P13725.
Species	Human
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	P13725
Synonyms	OSM,Oncostatin M,MGC20461
Construction	Ala26-Arg221
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	25.1 kDa (predicted). Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.