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Sapropterin dihydrochloride

Name: Sapropterin dihydrochloride
Brand: TargetMol
SKU: T7117
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T7117Cas No. 69056-38-8

Alias Sapropterin Hydrochloride, 6R-Tetrahydro-L-biopterin dihydrochloride, 6R-BH4 dihydrochloride

Sapropterin dihydrochloride (6R-BH4 dihydrochloride) is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.

Sapropterin dihydrochloride

🥰Excellent

Purity: 99.88%

Catalog No. T7117Alias Sapropterin Hydrochloride, 6R-Tetrahydro-L-biopterin dihydrochloride, 6R-BH4 dihydrochlorideCas No. 69056-38-8

Sapropterin dihydrochloride (6R-BH4 dihydrochloride) is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.

Pack Size	Price	Availability
5 mg	$31	In Stock
10 mg	$47	In Stock
50 mg	$79	In Stock
100 mg	$139	In Stock

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Batch Information

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Purity:99.88%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Sapropterin dihydrochloride (6R-BH4 dihydrochloride) is phenylalanine hydroxylase agonist that is approved for the treatment of BH4 responsive PKU.
Synonyms	Sapropterin Hydrochloride, 6R-Tetrahydro-L-biopterin dihydrochloride, 6R-BH4 dihydrochloride

Chemical Properties

Molecular Weight	314.17
Formula	C₉H₁₇Cl₂N₅O₃
Cas No.	69056-38-8
Smiles	Cl.Cl.C[C@H](O)[C@H](O)[C@H]1CNc2[nH]c(N)nc(=O)c2N1
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store under nitrogen,store at low temperature | Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 260 mg/mL (827.58 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	3.1830 mL	15.9150 mL	31.8299 mL	159.1495 mL
5 mM	0.6366 mL	3.1830 mL	6.3660 mL	31.8299 mL
10 mM	0.3183 mL	1.5915 mL	3.1830 mL	15.9150 mL
20 mM	0.1591 mL	0.7957 mL	1.5915 mL	7.9575 mL
50 mM	0.0637 mL	0.3183 mL	0.6366 mL	3.1830 mL
100 mM	0.0318 mL	0.1591 mL	0.3183 mL	1.5915 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc