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CXCR5 Protein-VLP, Human, Recombinant (Flag & His-Strep)
(Synonyms: MDR15, CD185, BLR1) Copy Product InfoSynonyms: MDR15, CD185, BLR1
Catalog No. TMPY-07151 Copy Product Info
CXCR5 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is P32302.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $582 | 7-10 days | 7-10 days | |
| 20 µg | $983 | 7-10 days | 7-10 days | |
| 50 µg | $1,490 | 7-10 days | 7-10 days | |
| 100 µg | $2,380 | 7-10 days | 7-10 days | |
| 200 µg | $3,590 | 7-10 days | 7-10 days | |
| 500 µg | $8,630 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized CXCR5 Protein-VLP, Human, Recombinant (Flag & His-Strep) (Cat#TMPY-07151) at 5 μg/mL (100 μL/well) can bind Anti- CXCR5 Monoclonal Antibody, Human IgG1, the EC50 is 1-5 ng/mL. |
| Description | CXCR5 Protein-VLP, Human, Recombinant (Flag & His-Strep) is expressed in HEK293 Cells. The accession number is P32302. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-Flag, C-His-Strep |
| Accession Number | P32302 |
| Construction | A DNA sequence encoding the Human CXCR5 (P32302) (Met1-Phe372) was expressed, with a Flag tag at the N-terminus, a polyhistidine tag and a strep tag at the C-terminus. |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as sterile 50 mM Hepes, 150 mM NaCl, 10% Trehalose, pH 7.2. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Synonyms | MDR15, CD185, BLR1 |
| Research Background | Because of the level of attention it received due to its role as the principal HIV coreceptor, CCR5 has been described as a 'celebrity' chemokine receptor. The wealth of CCR5-related tools that have been developed during the intensive investigation of CCR5 as an HIV drug target can now be turned towards the study of CCR5 as a model chemokine receptor. The enforced expression of CXCR5 onto Treg cells efficiently induces Tfr cell-like properties, which might be a promising cellular therapeutic approach for the treatment of antibody-mediated autoimmune diseases. The Chemokine receptor 5 (CCR5) is implicated in immune cell migration and cytokine release in the CNS, and it was demonstrated to strongly contribute to CNS inflammation and damage in several models of sterile and pathogen-mediated CNS diseases. |
| Molecular Weight | 45.84 kDa (predicted) |
| Shipping | Proteins are shipped with blue ice. |
| Storage | Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
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Related Tags: CXCR5 Protein-VLP, Human, Recombinant (Flag & His-Strep) chemical structure | CXCR5 Protein-VLP, Human, Recombinant (Flag & His-Strep) molecular weight
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