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Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79)
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Catalog No. TMAY-01579
Alias RCCP2, HGFR, DFNB97, DA11, c-Met, AUTS9
Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) is a Rabbit antibody targeting Phospho-Met (Tyr1234, 1235). Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) can be used in WB.
Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79)
Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79)
😃Good
Catalog No. TMAY-01579Alias RCCP2, HGFR, DFNB97, DA11, c-Met, AUTS9
Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) is a Rabbit antibody targeting Phospho-Met (Tyr1234, 1235). Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $81 | 7-10 days | |
| 100 μL | $233 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) is a Rabbit antibody targeting Phospho-Met (Tyr1234, 1235). Anti-Phospho-Met (Tyr1234, 1235) Antibody (9K79) can be used in WB. |
| Alias | RCCP2, HGFR, DFNB97, DA11, c-Met, AUTS9 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 9K79 |
| Reactivity | Human;
Predicted to React with:Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus, Rabbit |
| Verified Activity | 1. Western blot analysis of extracts from serum-starved A549, untreated (line A); treated with HGF (50 ng/mL, 5min; +) (line B); treated with HGF and λ-phosphatase (line C) using Phospho-Met(Tyr1234, 1235) rabbit monoclonal Antibody at 1:1000 dilution. (Validation Experiment) 2. Western blot analysis of extracts from A549, untreated (line A) or treated with HGF (50 ng/mL, 5min; +) (line B), using Phospho-Met (Tyr1234, 1235) rabbit monoclonal Antibody at 1:1000 dilution (upper) or Anti-Actin Antibody, Rabbit Monoclonal at 1:50000 dilution (lower). |
| Application | WB |
| Recommended Dose | WB: 1:1000-1:5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to residues around (Tyr1234, 1235) of Human Phospho-Met. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Research Background | Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is overexpressed and/or mutated in a variety of malignancies. HGFR protein is produced as a single-chain precursor, and HGF is the only known ligand. Normal HGF/HGFR signaling is essential for embryonic development, tissue repair, or wound healing, whereas aberrantly active HGFR has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes. HGFR protein is a multifaceted regulator of growth, motility, and invasion, and is normally expressed by cells of epithelial origin. Preclinical studies suggest that targeting aberrant HGFR signaling could be an attractive therapy in cancer.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide corresponding to residues around (Tyr1234, 1235) of Human Phospho-Met |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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