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Anti-IL-13RA1 Antibody-APC (9F921) is a APC-conjugated Rabbit antibody targeting IL-13RA1. Anti-IL-13RA1 Antibody-APC (9F921) can be used in FCM.
Description | Anti-IL-13RA1 Antibody-APC (9F921) is a APC-conjugated Rabbit antibody targeting IL-13RA1. Anti-IL-13RA1 Antibody-APC (9F921) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 9F921 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of anti-human IL13RA1(CD213a1) on MCF-7 cells. MCF-7 cells were stained with APC-anti human IL13RA1(CD213a1)(solid line) or APC-rabbit isotype control (dashed line). |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL13RA1 / IL-13RA1 (rh IL13RA1 / IL-13RA1; TMPY-01258; NP_001551.1; Met1-Thr343) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2 and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3, and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
Conjucates | APC |
Others Formats | PE |
Antibody Types Available | 2 |
Immunogen | Recombinant Human IL13RA1 / IL-13RA1 protein (TMPY-01258) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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