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CCR8 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His)

(Synonyms: TER1, GPR-CY6, GPRCY6, CY6, CMKBRL2, CMKBR8, CKR-L1, CKRL1, CDw198, CCR-8, CC-CKR-8) Copy Product Info

Synonyms: TER1, GPR-CY6, GPRCY6, CY6, CMKBRL2, CMKBR8, CKR-L1, CKRL1, CDw198, CCR-8, CC-CKR-8

Catalog No. TMPY-07066 Copy Product Info
CCR8 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) is expressed in HEK293 Cells. The accession number is P51685.
CCR8 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His)
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Pack SizePriceUSA StockGlobal StockQuantity
5 μg$7487-10 days7-10 days
10 μg$1,2607-10 days7-10 days
20 μg$2,1507-10 days7-10 days
50 μg$4,3907-10 days7-10 days
100 μg$7,5607-10 days7-10 days
200 μg$9,8707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
1. Immobilized CCR8 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) (Cat#TMPY-07066) at 5 μg/mL (100 μL/well) can bind Anti- Human CCR8 Monoclonal Antibody1, Human IgG1, the  EC50 is 1-5 ng/mL (QC tested).
2. Immobilized CCR8 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) (Cat#TMPY-07066) at 5 μg/mL (100 μL/well) can bind Anti- Human CCR8 Monoclonal Antibody2, Human IgG1, the  EC50 is 3-10 ng/mL (Routinely tested).
3. Immobilized CCR8 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) (Cat#TMPY-07066) at 5 μg/mL (100 μL/well) can bind Anti- Human CCR8 Monoclonal Antibody3, Human IgG1, the  EC50 is 3-10 ng/mL (Routinely tested).
Description
CCR8 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) is expressed in HEK293 Cells. The accession number is P51685.
Species
Human
Expression System
HEK293 Cells
TagN-Flag-Strep, C-His
Accession NumberP51685
ConstructionA DNA sequence encoding the Human CCR8 (P51685)(Met1-Cys228) & (Asn230-Ser318) was expressed and linked by a Fusion Protein, with a Flag tag followed by a Strep Tag at the N-terminus, a polyhistidine tag at the C-terminus. Within the expressed regions, there are several proprietary thermostabilizing mutations.This protein was prepared using our Nanodisc platform. Nanodisc is a versatile tool for studying membrane proteins. Using styrene-maleic acid (SMA) copolymer, membrane proteins can be extracted directly from prokaryotic and eukaryotic expression systems in the absence of detergents to preserve the protein structure and function better. Compared to membrane scaffold proteins (MSPs) nanodiscs, SMA nanodiscs also have the advantage of preserving proteins' nature by maintaining native lipids surrounded without introducing any heterologous proteins, which allows studies of protein structure and functions in a native-like environment.
Protein Purity
≥ 85% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as sterile 50 mM HEPES, 150 mM NaCl, pH 7.5. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability & StorageSamples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
ShippingProteins are shipped with blue ice.
SynonymsTER1, GPR-CY6, GPRCY6, CY6, CMKBRL2, CMKBR8, CKR-L1, CKRL1, CDw198, CCR-8, CC-CKR-8
Chemical Properties
Molecular Weight46.51 kDa (predicted); 96.9 kDa (dimer) and 44 kDa (reducing contition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: CCR8 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) chemical structure | CCR8 Protein-Nanodisc, Human, Recombinant (Flag-Strep & His) molecular weight