store at low temperature,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB gene in P. aeruginosa, the secretion of the metabolites pyocyanin and the lectin PA-IL, as well as increasing biofilm production in P. aeruginosa populations. It also reduces the iron content of the P. aeruginosa growth medium when used at a concentration of 40 μM and acts as an iron chelator in iron sulphate solutions.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 77.00 | |
10 mg | In stock | $ 95.00 | |
25 mg | In stock | $ 161.00 | |
50 mg | In stock | $ 240.00 | |
100 mg | In stock | $ 380.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 75.00 |
Description | 2-heptyl-3-hydroxy-4(1H)-Quinolone (Pseudomonas Quinolone Signal) is a quorum-sensing signalling molecule produced by Pseudomonas aeruginosa in response to increased cell density. It increases the expression of the lasB gene in P. aeruginosa, the secretion of the metabolites pyocyanin and the lectin PA-IL, as well as increasing biofilm production in P. aeruginosa populations. It also reduces the iron content of the P. aeruginosa growth medium when used at a concentration of 40 μM and acts as an iron chelator in iron sulphate solutions. |
In vitro |
2-heptyl-3-hydroxy-4(1H)-Quinolone (60 µM) increases secretion of the metabolite pyocyanin and the lectin PA-IL, as well as increases biofilm production in P. aeruginosa populations.[2] 2-heptyl-3-hydroxy-4(1H)-Quinolone (40 µM) reduces iron levels in P. aeruginosa growth media when used at a concentration and acts as an iron chelator in a Fe(III)-sulfate solution.[3] |
Synonyms | 2-heptyl-3-hydroxy-4(1H)-Quinolone, PQS, Pseudomonas Quinolone Signal |
Molecular Weight | 259.34 |
Formula | C16H21NO2 |
CAS No. | 108985-27-9 |
store at low temperature,store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Methanol: Soluble
DMSO: 12 mg/mL (46.27 mM)
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2-heptyl-3-hydroxy-4(1H)-Quinolone 108985-27-9 Others PQS Pseudomonas Quinolone Signal inhibitor inhibit