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Anti-SLC40A1 Polyclonal Antibody 2 is a Rabbit antibody targeting SLC40A1. Anti-SLC40A1 Polyclonal Antibody 2 can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-SLC40A1 Polyclonal Antibody 2 is a Rabbit antibody targeting SLC40A1. Anti-SLC40A1 Polyclonal Antibody 2 can be used in WB. |
| Synonyms | Solute carrier family 40 member 1, SLC11A3, S40A1, MTP1, MSTP079, MST079, Iron regulated transporter 1, IREG1, HFE4, FPN1, Ferroportin-1 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Rabbit) |
| Verified Activity | 1. Sample: K562 (Human) Cell Lysate at 30 μg HepG2 (Human) Cell Lysate at 30 μg Primary: Anti-SLC40A1 (TMAB-01724) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 63 kDa Observed band size: 63 kDa 2. Sample: A673 (Human) Cell Lysate at 30 μg Primary: Anti-SLC40A1 (TMAB-01724) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 63 kDa Observed band size: 65 kDa 3. Sample: Lane 1: Human Hepg2 cell lysates Lane 2: Human K562 cell lysates Lane 3: Human Molt-4 cell lysates Lane 4: Human Jurkat cell lysates Primary: Anti-SLC40A1 (TMAB-01724) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 63 kDa Observed band size: 60 kDa ![]() ![]() ![]() |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. Note=Localized to the basolateral membrane of polarized epithelial cells. |
| Tissue Specificity | Expressed in placenta, intestine, muscle and spleen. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin. |
| Immunogen | KLH conjugated synthetic peptide: human SLC40A1/FPN1 |
| Antigen Species | Human |
| Gene Name | SLC40A1 |
| Gene ID | |
| Protein Name | Solute carrier family 40 member 1 |
| Uniprot ID | |
| Biology Area | Vitamins / minerals,Vitamins / Minerals |
| Function | May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). |
| Molecular Weight | Theoretical: 63 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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