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Anti-Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III) Antibody (7A890) is a Rabbit antibody targeting Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III). Anti-Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III) Antibody (7A890) can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $94 | 7-10 days | |
100 μL | $293 | 7-10 days |
Description | Anti-Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III) Antibody (7A890) is a Rabbit antibody targeting Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III). Anti-Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain III) Antibody (7A890) can be used in WB. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 7A890 |
Verified Activity | Anti-Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E / Envelope protein (Domain III) rabbit monoclonal antibody at 1:2000 dilution -Sample:Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E / Envelope protein (Domain III,His Tag ) -Lane A: 5ng -Secondary -Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. |
Application | WB |
Recommended Dose | WB: 1:2000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E / Envelope protein (Domain III) ( TMPY-04868; ALU33341.1; Val593-Lys699). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Envelope of Zika virus is responsible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH215 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent with those reported for dengue, YFYF and Japanese encephalitis. The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross-reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross-reactivity with dengue and YF.Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus. |
Conjucates | Unconjugated |
Immunogen | Recombinant Zika virus (ZIKV) (strain Zika SPH2015) ZIKV-E / Envelope protein (Domain III) Protein (TMPY-04868) |
Antigen Species | ZIKV |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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