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Salcaprozate sodium

Name: Salcaprozate sodium
Brand: TargetMol
SKU: T8926
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T8926Cas No. 203787-91-1

Alias SNAC

Salcaprozate sodium (SNAC), an oral absorption promoter, enhances passive transcellular permeation through small intestinal epithelia, making it a potent delivery agent for oral heparin and insulin by increasing lipophilicity via non-covalent macromolecule complexation.

Salcaprozate sodium

🥰Excellent

Purity: 99.75%

Catalog No. T8926Alias SNACCas No. 203787-91-1

Pack Size	Price	Availability
500 mg	$36	In Stock
1 g	$58	In Stock
2 g	$82	In Stock
5 g	$133	In Stock
10 g	$188	In Stock
25 g	$329	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Purity:99.75%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Salcaprozate sodium (SNAC), an oral absorption promoter, enhances passive transcellular permeation through small intestinal epithelia, making it a potent delivery agent for oral heparin and insulin by increasing lipophilicity via non-covalent macromolecule complexation.
In vitro	Salcaprozate sodium(SNAC ;12.5-400 μg/mL;?24 h) has no toxicity to Caco-2 cells, and the survival percentage is above 90% when SNAC is 200 μg/mL.?SNAC (50 and 200 μg/mL) improves the apparent permeability coeffcient (Papp) of RA and SA-B by 2.14-fold and 3.68-fold compared with the Papp of SAs solution[1].
Synonyms	SNAC

Chemical Properties

Molecular Weight	301.32
Formula	C₁₅H₂₀NNaO₄
Cas No.	203787-91-1
Smiles	C1=CC=C(C(=C1)C(=O)NCCCCCCCC(=O)[O-])O.[Na+]
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (331.88 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (13.27 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3187 mL	16.5937 mL	33.1873 mL	165.9365 mL
5 mM	0.6637 mL	3.3187 mL	6.6375 mL	33.1873 mL
10 mM	0.3319 mL	1.6594 mL	3.3187 mL	16.5937 mL
20 mM	0.1659 mL	0.8297 mL	1.6594 mL	8.2968 mL
50 mM	0.0664 mL	0.3319 mL	0.6637 mL	3.3187 mL
100 mM	0.0332 mL	0.1659 mL	0.3319 mL	1.6594 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc