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Protein kinase inhibitor H-7 dihydrochloride

🥰Excellent
Catalog No. T22831Cas No. 108930-17-2
Alias H-7 dihydrochloride

Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) inhibited PMA-induced promiscuity cell lysis activity.

Protein kinase inhibitor H-7 dihydrochloride
Other Forms of Protein kinase inhibitor H-7 dihydrochloride:

Protein kinase inhibitor H-7 dihydrochloride

🥰Excellent
Purity: 99.54%
Catalog No. T22831Alias H-7 dihydrochlorideCas No. 108930-17-2
Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) inhibited PMA-induced promiscuity cell lysis activity.
Pack SizePriceAvailabilityQuantity
10 mg$32In Stock
25 mg$68In Stock
50 mg$111In Stock
100 mg$177In Stock
200 mg$258In Stock
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Purity:99.54%
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Product Introduction

Bioactivity
Description
Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) inhibited PMA-induced promiscuity cell lysis activity.
SynonymsH-7 dihydrochloride
Chemical Properties
Molecular Weight364.29
FormulaC14H19Cl2N3O2S
Cas No.108930-17-2
SmilesCl.Cl.CC1CNCCN1S(=O)(=O)c1cccc2cnccc12
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (150.98 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.7451 mL13.7253 mL27.4507 mL137.2533 mL
5 mM0.5490 mL2.7451 mL5.4901 mL27.4507 mL
10 mM0.2745 mL1.3725 mL2.7451 mL13.7253 mL
20 mM0.1373 mL0.6863 mL1.3725 mL6.8627 mL
50 mM0.0549 mL0.2745 mL0.5490 mL2.7451 mL
100 mM0.0275 mL0.1373 mL0.2745 mL1.3725 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

PKCH7 DihydrochlorideH-7H7H 7 DihydrochlorideH 7
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