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Pleuromutilin

Name: Pleuromutilin
Brand: TargetMol
SKU: T16552
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T16552Cas No. 125-65-5

Alias Mutilin 14-glycolate, Drosophilin B

Pleuromutilin (Drosophilin B) is an inhibitor of bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.

Pleuromutilin

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Purity: 97.321%

Catalog No. T16552Alias Mutilin 14-glycolate, Drosophilin BCas No. 125-65-5

Pleuromutilin (Drosophilin B) is an inhibitor of bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.

Pack Size	Price	Availability
2 mg	$34	In Stock
5 mg	$53	In Stock
10 mg	$74	In Stock
25 mg	$81	In Stock
50 mg	$85	In Stock
100 mg	$95	In Stock
500 mg	$108	In Stock
1 g	$158	In Stock
1 mL x 10 mM (in DMSO)	$59	In Stock

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Batch Information

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Purity:97.321%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Pleuromutilin (Drosophilin B) is an inhibitor of bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria.
Synonyms	Mutilin 14-glycolate, Drosophilin B

Chemical Properties

Molecular Weight	378.5
Formula	C₂₂H₃₄O₅
Cas No.	125-65-5
Smiles	C[C@@H]1[C@]23[C@]([C@](C)([C@H](OC(CO)=O)C[C@](C=C)(C)[C@H]1O)[C@H](C)CC2)(C(=O)CC3)[H]
Relative Density.	1.15 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (264.2 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6420 mL	13.2100 mL	26.4201 mL	132.1004 mL
5 mM	0.5284 mL	2.6420 mL	5.2840 mL	26.4201 mL
10 mM	0.2642 mL	1.3210 mL	2.6420 mL	13.2100 mL
20 mM	0.1321 mL	0.6605 mL	1.3210 mL	6.6050 mL
50 mM	0.0528 mL	0.2642 mL	0.5284 mL	2.6420 mL
100 mM	0.0264 mL	0.1321 mL	0.2642 mL	1.3210 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc