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MPZL1 Protein, Human, Recombinant (His)

(Synonyms: transcript variant 1, Myelin protein zero-like 1, mRNA, isoform CRA_b, Homo sapiens myelin protein zero-like 1 (MPZL1), highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1), FLJ96614, cDNA FLJ78597, cDNA) Copy Product Info

Synonyms: transcript variant 1, Myelin protein zero-like 1, mRNA, isoform CRA_b, Homo sapiens myelin protein zero-like 1 (MPZL1), highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1), FLJ96614, cDNA FLJ78597, cDNA

Catalog No. TMPJ-00712 Copy Product Info
Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.
MPZL1 Protein, Human, Recombinant (His)
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$397-10 days7-10 days
10 μg$607-10 days7-10 days
20 μg$837-10 days7-10 days
50 μg$1297-10 days7-10 days
100 μg$2197-10 days7-10 days
200 μg$3837-10 days7-10 days
500 μg$8067-10 days7-10 days
1 mg$1,3007-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 95% as determined by reducing SDS-PAGE.
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.
Species
Human
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberO95297
Amino AcidSer36-Val162
ConstructionSer36-Val162
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonymstranscript variant 1, Myelin protein zero-like 1, mRNA, isoform CRA_b, Homo sapiens myelin protein zero-like 1 (MPZL1), highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1), FLJ96614, cDNA FLJ78597, cDNA
Research Background
Chemical Properties
Molecular Weight20-28 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: MPZL1 Protein, Human, Recombinant (His) chemical structure | MPZL1 Protein, Human, Recombinant (His) molecular weight