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MPZL1 Protein, Human, Recombinant (His)

Catalog No. TMPJ-00712
Synonyms: FLJ96614, mRNA, Myelin protein zero-like 1, cDNA FLJ78597, cDNA, Homo sapiens myelin protein zero-like 1 (MPZL1), isoform CRA_b, highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1), transcript variant 1

Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
MPZL1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 60.00
50 μg 5 days $ 129.00
500 μg 5 days $ 806.00
1 mg 5 days $ 1,300.00
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Biological Description
Technical Params
Product Properties
Description Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.
Species Human
Expression System Human Cells
Tag C-6His
Accession Number O95297
Synonyms FLJ96614, mRNA, Myelin protein zero-like 1, cDNA FLJ78597, cDNA, Homo sapiens myelin protein zero-like 1 (MPZL1), isoform CRA_b, highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1), transcript variant 1
Amino Acid Ser36-Val162
Construction Recombinant Human Myelin Protein P0-like 1 is produced by our Mammalian expression system and the target gene encoding Ser36-Val162 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 20-28 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.

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Keywords

MPZL1 Protein, Human, Recombinant (His) cDNA FLJ-78597 MPZL1 FLJ96614 FLJ-96614 mRNA Myelin protein zero-like 1 cDNA FLJ78597 cDNA FLJ 78597 cDNA Homo sapiens myelin protein zero-like 1 (MPZL1) Homo sapiens myelin protein zero-like 1 FLJ 96614 isoform CRA_b MPZL 1 highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1) transcript variant 1 MPZL-1 recombinant recombinant-proteins proteins protein

 

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