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SLPI Protein, Human, Recombinant (hFc)

Catalog No. TMPK-00767
Synonyms: WFDC4, HUSI, SLPI, WAP4, MPI, BLPI, ALK1, HUSI-1, ALP

Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation of the response to LPS (lipopolysaccharide) stimulation. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites, and have been shown to be modulated in multiple pathological conditions.

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SLPI Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 371.00
500 μg 5 days $ 1,490.00
1 mg 5 days $ 2,480.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation of the response to LPS (lipopolysaccharide) stimulation. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites, and have been shown to be modulated in multiple pathological conditions.
Species Human
Expression System HEK293
Tag C-hFc
Accession Number P03973
Synonyms WFDC4, HUSI, SLPI, WAP4, MPI, BLPI, ALK1, HUSI-1, ALP
Construction Recombinant Human SLPI Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Ser26-Ala132.[Accession |P03973]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 38.5 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Supplied as 0.22μm filtered solution in PBS, 350mM NaCl (pH 7.4).
Stability & Storage

Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation of the response to LPS (lipopolysaccharide) stimulation. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites, and have been shown to be modulated in multiple pathological conditions.

References and Literature

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Keywords

SLPI Protein, Human, Recombinant (hFc) HUSI1 WFDC4 WAP 4 HUSI WFDC-4 ALK 1 SLPI HUSI 1 WAP4 WFDC 4 MPI ALK-1 BLPI ALK1 WAP-4 HUSI-1 ALP recombinant recombinant-proteins proteins protein

 

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