Shopping Cart
Remove All
Your shopping cart is currently empty
LPA1 receptor antagonist 1
Copy Product Info
🥰Excellent
Catalog No. T15785Cas No. 1396006-71-5
Alias LPA1 R antagonist 1
LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopathic pulmonary fibrosis.
LPA1 receptor antagonist 1
Copy Product Info🥰Excellent
Purity: 99.56%
Catalog No. T15785Alias LPA1 R antagonist 1Cas No. 1396006-71-5
LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopathic pulmonary fibrosis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $88 | In Stock | In Stock | |
| 5 mg | $220 | In Stock | In Stock | |
| 10 mg | $352 | In Stock | In Stock | |
| 25 mg | $551 | In Stock | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:99.56%
Appearance:Solid
Color:White
Contact us for more batch information
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopathic pulmonary fibrosis. |
| Targets&IC50 | LPA1:25 nM |
| In vitro | Compared to Ki16425 and AM095, LPA1 receptor antagonist 1 demonstrates superior anti-proliferative activity. It exhibits the highest selectivity for LPA1 and efficiently inhibits LPA-induced NHLF proliferation and contraction[1]. Similarly, LPA1 receptor antagonist 1 (compound 2) shows highly specific inhibitory activity against LPA1, with minimal inhibition of LPA3 even at relatively high concentrations.[1]. |
| In vivo | Oral administration of LPA1 receptor antagonist 1 (compound 2) to mice led to a dose-dependent reduction in plasma histamine levels in a murine LPA challenge model [1]. |
| Synonyms | LPA1 R antagonist 1 |
| Molecular Weight | 482.53 |
| Formula | C28H26N4O4 |
| Cas No. | 1396006-71-5 |
| Smiles | C(O)(=O)C1(CC1)C2=CC=C(C=C2)C3=CC=C(C=C3)N4C(NC(O[C@H](C)C5=CC=CC=C5)=O)=C(C)N=N4 |
| Relative Density. | 1.31 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy LPA1 receptor antagonist 1 | purchase LPA1 receptor antagonist 1 | LPA1 receptor antagonist 1 cost | order LPA1 receptor antagonist 1 | LPA1 receptor antagonist 1 chemical structure | LPA1 receptor antagonist 1 in vivo | LPA1 receptor antagonist 1 in vitro | LPA1 receptor antagonist 1 formula | LPA1 receptor antagonist 1 molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.