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PPZ-A10

🥰Excellent
Catalog No. T84818Cas No. 2941268-67-1
Alias PPZA10

PPZ-A10 is an ionisable cationic lipid suitable for synthesising lipid nanoparticles (LNPs) to deliver siRNA and mRNA in vitro and in vivo.

PPZ-A10

PPZ-A10

🥰Excellent
Purity: 97.22%
Catalog No. T84818Alias PPZA10Cas No. 2941268-67-1
PPZ-A10 is an ionisable cationic lipid suitable for synthesising lipid nanoparticles (LNPs) to deliver siRNA and mRNA in vitro and in vivo.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$53-In Stock
5 mg$116-In Stock
10 mg$190-In Stock
25 mg$380-In Stock
50 mg$614-In Stock
100 mg$979-In Stock
1 mL x 10 mM (in DMSO)$190-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:97.22%
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Product Introduction

Bioactivity
Description
PPZ-A10 is an ionisable cationic lipid suitable for synthesising lipid nanoparticles (LNPs) to deliver siRNA and mRNA in vitro and in vivo.
SynonymsPPZA10
Chemical Properties
Molecular Weight903.54
FormulaC56H114N6O2
Cas No.2941268-67-1
SmilesO=C(NCCCN1CCN(CC1)CCCNC(=O)CCN(CCCCCCCCCC)CCCCCCCCCC)CCN(CCCCCCCCCC)CCCCCCCCCC
ColorYellow
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 80 mg/mL (88.54 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.1068 mL5.5338 mL11.0676 mL55.3379 mL
5 mM0.2214 mL1.1068 mL2.2135 mL11.0676 mL
10 mM0.1107 mL0.5534 mL1.1068 mL5.5338 mL
20 mM0.0553 mL0.2767 mL0.5534 mL2.7669 mL
50 mM0.0221 mL0.1107 mL0.2214 mL1.1068 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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