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MOG peptide (35-55) amide
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Catalog No. T78031Cas No. 2022956-48-3
MOG peptide (35-55) amide, a myelin oligodendrocyte glycoprotein (MOG) fragment spanning amino acids 35 to 55, selectively stimulates CD4+ T cell expansion and induces experimental autoimmune encephalomyelitis (EAE) in animal models [1] [2] [3].
MOG peptide (35-55) amide
😃Good
Catalog No. T78031Cas No. 2022956-48-3
MOG peptide (35-55) amide, a myelin oligodendrocyte glycoprotein (MOG) fragment spanning amino acids 35 to 55, selectively stimulates CD4+ T cell expansion and induces experimental autoimmune encephalomyelitis (EAE) in animal models [1] [2] [3].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $76 | 7-10 days | |
| 5 mg | $178 | 7-10 days | |
| 10 mg | $278 | 7-10 days | |
| 25 mg | $518 | 7-10 days | |
| 50 mg | $798 | 7-10 days |
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Product Introduction
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Chemical Properties
| Description | MOG peptide (35-55) amide, a myelin oligodendrocyte glycoprotein (MOG) fragment spanning amino acids 35 to 55, selectively stimulates CD4+ T cell expansion and induces experimental autoimmune encephalomyelitis (EAE) in animal models [1] [2] [3]. |
| In vitro | The expanded CD4+ T cells predominantly target the immunogenic peptide 35-55 of myelin oligodendrocyte glycoprotein (MOG35-55). In contrast, clonally expanded CD8+ T cells exhibit no response to myelin-derived peptides or proteins [1]. |
| In vivo | Administration of MOG peptide (35-55) at a concentration of 3 mg/mL (0.1 mL, s.c., single dose) actively induces experimental autoimmune encephalomyelitis (EAE) in mice [2]. Additionally, a single subcutaneous dose of MOG peptide (35-55) at 200 μg results in an increased level of the eosinophil chemoattractant eotaxin-1 in the spinal cord during EAE progression in C57BL/6 mice [3]. |
| Molecular Weight | 2580.97 |
| Formula | C118H178N36O28S |
| Cas No. | 2022956-48-3 |
| Sequence | Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-NH2 |
| Sequence Short | MEVGWYRSPFSRVVHLYRNGK-NH2 |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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