keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MOG peptide (35-55), a myelin oligodendrocyte glycoprotein (MOG) fragment spanning amino acids 35 to 55, selectively stimulates CD4+ T cell expansion and induces experimental autoimmune encephalomyelitis (EAE) in animal models [1] [2] [3].
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Description | MOG peptide (35-55), a myelin oligodendrocyte glycoprotein (MOG) fragment spanning amino acids 35 to 55, selectively stimulates CD4+ T cell expansion and induces experimental autoimmune encephalomyelitis (EAE) in animal models [1] [2] [3]. |
In vitro | The expanded CD4+ T cells predominantly target the immunogenic peptide 35-55 of myelin oligodendrocyte glycoprotein (MOG35-55). In contrast, clonally expanded CD8+ T cells exhibit no response to myelin-derived peptides or proteins [1]. |
In vivo | Administration of MOG peptide (35-55) at a concentration of 3 mg/mL (0.1 mL, s.c., single dose) actively induces experimental autoimmune encephalomyelitis (EAE) in mice [2]. Additionally, a single subcutaneous dose of MOG peptide (35-55) at 200 μg results in an increased level of the eosinophil chemoattractant eotaxin-1 in the spinal cord during EAE progression in C57BL/6 mice [3]. |
Molecular Weight | 2580.97 |
Formula | C118H178N36O28S |
CAS No. | 2022956-48-3 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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MOG peptide (35-55) 2022956-48-3 inhibitor inhibit