IL-11 Protein, Mouse, Recombinant

Name: IL-11 Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPY-04178
Rating: 4.5 (1 reviews)

(Synonyms: interleukin 11, IL-11) Copy Product Info

Synonyms: interleukin 11, IL-11

Catalog No. TMPY-04178 Copy Product Info

Purity: 96.5%

IL-11 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.2 kDa and the accession number is A3KPB8.

Pack Size	Price	USA Stock	Global Stock
5 µg	$79	7-10 days	7-10 days
10 µg	$127	In Stock	In Stock
20 µg	$192	7-10 days	7-10 days
100 µg	$773	7-10 days	7-10 days
200 µg	$1,320	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:96.5%

Appearance:Lyophilized powder

Color:White

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COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured in a cell proliferation assay using T1165 mouse plasmacytoma cells. The ED50 for this effect is typically 3-15 ng/ml.
Description	IL-11 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.2 kDa and the accession number is A3KPB8.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	A3KPB8
Construction	A DNA sequence encoding the mouse Il11 (NP_032376.1) (Pro22-Leu199) was expressed. Predicted N terminal: Pro
Protein Purity	> 95 % as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.15 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	interleukin 11, IL-11
Research Background	IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute-phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation, and could be used as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization.

Chemical Properties

Molecular Weight

19.2 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.