Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

m7GTP sodium

🥰Excellent
Catalog No. T75264
Alias 7-Methyl-guanosine-5'-triphosphate sodium

m7GTP sodium (7-Methyl-guanosine-5'-triphosphate sodium) is a structural analog of the mRNA cap that inhibits protein synthesis in vitro by binding to eIF4E (eukaryotic translation initiation factor), and is commonly used to study protein synthesis involving mRNA.

m7GTP sodium

m7GTP sodium

🥰Excellent
Catalog No. T75264Alias 7-Methyl-guanosine-5'-triphosphate sodium
m7GTP sodium (7-Methyl-guanosine-5'-triphosphate sodium) is a structural analog of the mRNA cap that inhibits protein synthesis in vitro by binding to eIF4E (eukaryotic translation initiation factor), and is commonly used to study protein synthesis involving mRNA.
Pack SizePriceAvailabilityQuantity
2 mg$118In Stock
Add to Cart
Add to Quotation
Bulk & Custom
Questions
View More
Select Batch
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
m7GTP sodium (7-Methyl-guanosine-5'-triphosphate sodium) is a structural analog of the mRNA cap that inhibits protein synthesis in vitro by binding to eIF4E (eukaryotic translation initiation factor), and is commonly used to study protein synthesis involving mRNA.
In vitro
m7GTP sodium acts as a competitive inhibitor of the eukaryotic translation initiation factor eIF4E. In various in vitro assays, m7GTP sodium is commonly used to block cap-dependent translation. For example, at 200 μM, m7GTP sodium effectively inhibits the binding of eIF4E to capped mRNAs in cell-free systems or lysates, impairing translation initiation[1].
Alias7-Methyl-guanosine-5'-triphosphate sodium
Chemical Properties
Molecular WeightC11H18N5O14P3.xNa
FormulaC11H18N5O14P3.xNa
SmilesCN1C=[N+](C2=C1C(=O)NC(=N2)N)C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])[O-])O)O.[Na+] xNa
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
H2O: 200 mg/mL, Sonication is recommended.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy m7GTP sodium | purchase m7GTP sodium | m7GTP sodium cost | order m7GTP sodium | m7GTP sodium chemical structure | m7GTP sodium in vitro | m7GTP sodium formula | m7GTP sodium molecular weight