ERO1L Protein, Human, Recombinant (His)

Name: ERO1L Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-01274
Rating: 4.5 (1 reviews)

(Synonyms: Oxidoreductin-1-L-α, Oxidoreductin-1-L-Alpha, ERO1-L-α, ERO1-Like Protein α, ERO1-Like Protein Alpha, ERO1-L-Alpha, ERO1-L, ERO1L, Endoplasmic Oxidoreductin-1-Like Protein) Copy Product Info

Synonyms: Oxidoreductin-1-L-α, Oxidoreductin-1-L-Alpha, ERO1-L-α, ERO1-Like Protein α, ERO1-Like Protein Alpha, ERO1-L-Alpha, ERO1-L, ERO1L, Endoplasmic Oxidoreductin-1-Like Protein

Catalog No. TMPJ-01274 Copy Product Info

ERO1-Like Protein α (ERO1L) is an enzyme that belongs to the EROs family. ERO1L is expressed at high level in esophagus and upper digestive tract. ERO1L is an essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. ERO1L acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. It associates with ERP44, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. ERO1L may be responsible for a significant proportion of reactive oxygen species (ROS) in the cell. ERO1L responses to temperature stimulus, protein thiol-disulfide exchange, protein folding with or without chaperone cofactor and transport.

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Pack Size	Price	USA Stock	Global Stock
5 μg	$112	35 days	35 days
10 μg	$183	35 days	35 days
20 μg	$292	35 days	35 days
50 μg	$545	35 days	35 days
100 μg	$792	35 days	35 days
200 μg	$1,150	35 days	35 days
500 μg	$1,900	35 days	35 days
1 mg	$2,730	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	ERO1-Like Protein α (ERO1L) is an enzyme that belongs to the EROs family. ERO1L is expressed at high level in esophagus and upper digestive tract. ERO1L is an essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. ERO1L acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. It associates with ERP44, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. ERO1L may be responsible for a significant proportion of reactive oxygen species (ROS) in the cell. ERO1L responses to temperature stimulus, protein thiol-disulfide exchange, protein folding with or without chaperone cofactor and transport.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	Q96HE7
Amino Acid	Glu24-His468
Construction	Glu24-His468
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonyms	Oxidoreductin-1-L-α, Oxidoreductin-1-L-Alpha, ERO1-L-α, ERO1-Like Protein α, ERO1-Like Protein Alpha, ERO1-L-Alpha, ERO1-L, ERO1L, Endoplasmic Oxidoreductin-1-Like Protein
Research Background

Chemical Properties

Molecular Weight

71 KDa (reducing condition)

Storage & Solubility Information

Storage

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: ERO1L Protein, Human, Recombinant (His) chemical structure | ERO1L Protein, Human, Recombinant (His) molecular weight