Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-TREM-2 Antibody-HRP (4H451)
🥰Excellent
Catalog No. TMAY-01617H
Anti-TREM-2 Antibody-HRP (4H451) is a HRP-conjugated Mouse antibody targeting TREM-2. Anti-TREM-2 Antibody-HRP (4H451) can be used in ELISA.
Anti-TREM-2 Antibody-HRP (4H451)
Anti-TREM-2 Antibody-HRP (4H451)
🥰Excellent
Catalog No. TMAY-01617H
Anti-TREM-2 Antibody-HRP (4H451) is a HRP-conjugated Mouse antibody targeting TREM-2. Anti-TREM-2 Antibody-HRP (4H451) can be used in ELISA.
Product information is being updated, if you want to purchase, please click the bulk custom button.
Bulk & Custom
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-TREM-2 Antibody-HRP (4H451) is a HRP-conjugated Mouse antibody targeting TREM-2. Anti-TREM-2 Antibody-HRP (4H451) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 4H451 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 0.1-1 μg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human TREM-2 / TREM2 (rh TREM-2 / TREM2; TMPY-01148; NP_061838.1; Met1-Ser174). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the basal ganglia, corpus callosum, medulla oblongata and spinal cord, and microglial cells are the major TREM2-producing cell type in the central nervous system (CNS). TREM2 may play a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. TREM2 forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells. It also associates with the signal adapter protein, DAP12, which has a cytoplasmic ITAM, leading to the subsequent activation of cytoplasmic tyrosine kinases. TREM2 is both required and sufficient for competent uptake of apoptotic neuronal cells. TREM2 and TREM2-L form a receptor-ligand pair connecting microglia with apoptotic neurons, directing removal of damaged cells to allow repair. Deficiency of the adapter protein DAP12 or its associated receptor TREM2 is associated with abnormal osteoclast development in humans. Defects in TREM2 are causes of PLOSL, also known as NHD. In addition, TREM2 signaling is also an important pathway to promote healing of wounds in the colon where stem cell replacement is necessary. |
| Conjucates | HRP |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Human TREM-2 / TREM2 Protein (TMPY-01148) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-TREM-2 Antibody-HRP (4H451) | purchase Anti-TREM-2 Antibody-HRP (4H451) | Anti-TREM-2 Antibody-HRP (4H451) cost | order Anti-TREM-2 Antibody-HRP (4H451)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.