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Anti-B2M/beta 2-Microglobulin Antibody-PE (8W936)

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Catalog No. TMAY-02176P

Anti-B2M/beta 2-Microglobulin Antibody-PE (8W936) is a PE-conjugated Mouse antibody targeting B2M/beta 2-Microglobulin. Anti-B2M/beta 2-Microglobulin Antibody-PE (8W936) can be used in FCM.

Anti-B2M/beta 2-Microglobulin Antibody-PE (8W936)

Anti-B2M/beta 2-Microglobulin Antibody-PE (8W936)

🥰Excellent
Catalog No. TMAY-02176P
Anti-B2M/beta 2-Microglobulin Antibody-PE (8W936) is a PE-conjugated Mouse antibody targeting B2M/beta 2-Microglobulin. Anti-B2M/beta 2-Microglobulin Antibody-PE (8W936) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-B2M/beta 2-Microglobulin Antibody-PE (8W936) is a PE-conjugated Mouse antibody targeting B2M/beta 2-Microglobulin. Anti-B2M/beta 2-Microglobulin Antibody-PE (8W936) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
Clone
8W936
Reactivity
Human
Verified Activity
Profile of peripheral blood lymphocytes analyzed by flow cytometry. The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable lymphocytes.
Application
FCM
Recommended Dose
1 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human B2M / beta-2 microglobulin (rh B2M / beta-2 microglobulin; TMPY-01686; NP_004039.1; Met 1-Met 119) and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Research BackgroundB2M, also known as β2-Microglobulin or CDABP0092, is a component of MHC class I molecules found expression in all nucleated cells (excludes red blood cells). The major function of MHC class I moleculesis is to display fragments of proteins from within the cell to T-cells and cells containing foreign proteins will be attacked. B2M (β2-Microglobulin) is a low molecular weight protein. It was demonstrated that B2M (β2-Microglobulin) was localized in the membranes of nucleated cells and was found to be associated with HL-A antigens. B2M (β2- Microglobulin) is present in free form in various body fluids and as a subunit of histocompatibility antigens on cell surfaces lateral to the α3 chain. Unlike α3, β2 has no transmembrane region. Directly above β2 lies the α1 chain, which itself is lateral to the α2. In the absence of B2M (β2 microglobulin), very limited amounts of MHC class I (classical and non-classical) molecules can be detected on the surface. In the absence of MHC class I, CD8 T cells, a subset of T cells involved in the development of acquired immunity cannot develop. Low levels of B2M (β2 microglobulin) can indicate non-progression of HIV.
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Unconjugated/FITC
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Human B2M / beta-2 microglobulin protein (TMPY-01686)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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