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CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated

(Synonyms: Interleukin-2 receptor subunit β, Interleukin-2 receptor subunit beta, IL2RB, IL-2R subunit β, IL-2R subunit beta, IL-2 receptor subunit β, IL-2 receptor subunit beta, High affinity IL-2 receptor subunit β, High affinity IL-2 receptor subunit beta, CD122) Copy Product Info

Synonyms: Interleukin-2 receptor subunit β, Interleukin-2 receptor subunit beta, IL2RB, IL-2R subunit β, IL-2R subunit beta, IL-2 receptor subunit β, IL-2 receptor subunit beta, High affinity IL-2 receptor subunit β, High affinity IL-2 receptor subunit beta, CD122

Catalog No. TMPJ-00326 Copy Product Info
Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.

Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.
Species
Human
Expression System
HEK293 Cells
TagC-6xHis-Avi
Accession NumberP14784
Amino AcidAla27-Asp239
ConstructionAla27-Asp239
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsInterleukin-2 receptor subunit β, Interleukin-2 receptor subunit beta, IL2RB, IL-2R subunit β, IL-2R subunit beta, IL-2 receptor subunit β, IL-2 receptor subunit beta, High affinity IL-2 receptor subunit β, High affinity IL-2 receptor subunit beta, CD122
Research Background
Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.
Chemical Properties
Molecular Weight35-45 KDa (reducing condition)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated chemical structure | CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated molecular weight