CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated

Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.

Pack Size	Availability	Price/USD	Quantity
20 μg	5 days	$ 355.00
100 μg	5 days	$ 963.00

Pack Size

Availability

Price/USD

Quantity

20 μg

5 days

$ 355.00

100 μg

5 days

$ 963.00

Description

Species	Human
Expression System	Human Cells
Tag	C-6His-Avi
Accession Number	P14784
Synonyms	IL-2R subunit beta, High affinity IL-2 receptor subunit β, Interleukin-2 receptor subunit β, High affinity IL-2 receptor subunit beta, Interleukin-2 receptor subunit beta, IL-2 receptor subunit β, IL2RB, CD122, IL-2R subunit β, IL-2 receptor subunit beta
Amino Acid	Ala27-Asp239
Construction	Biotinylated Recombinant Human Interleukin-2 Receptor subunit beta is produced by our Mammalian expression system and the target gene encoding Ala27-Asp239 is expressed with a 6His, Avi tag at the C-terminus.
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight	35-45 KDa, reducing conditions

Endotoxin	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Stability & Storage	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background	Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs.

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CD122/IL2RB Protein, Human, Recombinant (aa 27-239, His & Avi), Biotinylated

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