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Anti-Phospho-p53 (Ser315) Polyclonal Antibody

(Synonyms: p-p53 (Ser315), p-p53 (S315), p53 (p-Ser315), p53 (p-S315)) Copy Product Info
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Synonyms: p-p53 (Ser315), p-p53 (S315), p53 (p-Ser315), p53 (p-S315)

Catalog No. TMAC-02996 Copy Product Info
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Anti-Phospho-p53 (Ser315) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p53 (Ser315). Anti-Phospho-p53 (Ser315) Polyclonal Antibody can be used in IF,IHC,WB.
Anti-Phospho-p53
(Ser315) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2177-10 days7-10 days
100 μL$3167-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-p53 (Ser315) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p53 (Ser315). Anti-Phospho-p53 (Ser315) Polyclonal Antibody can be used in IF,IHC,WB.
Synonymsp-p53 (Ser315), p-p53 (S315), p53 (p-Ser315), p53 (p-S315)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundActs as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 315 (S-S-S(p)-P-Q) derived from Human p53
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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