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Anti-HSP70 Antibody (9E239)

😃Good
Catalog No. TMAY-01969
Alias heat shock 70kDa protein 1A

Anti-HSP70 Antibody (9E239) is a Mouse antibody targeting HSP70. Anti-HSP70 Antibody (9E239) can be used in IHC-P.

Anti-HSP70 Antibody (9E239)

Anti-HSP70 Antibody (9E239)

😃Good
Catalog No. TMAY-01969Alias heat shock 70kDa protein 1A
Anti-HSP70 Antibody (9E239) is a Mouse antibody targeting HSP70. Anti-HSP70 Antibody (9E239) can be used in IHC-P.
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100 μL189 € 7-10 days
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Product Introduction

Bioactivity
Description
Anti-HSP70 Antibody (9E239) is a Mouse antibody targeting HSP70. Anti-HSP70 Antibody (9E239) can be used in IHC-P.
Aliasheat shock 70kDa protein 1A
Ig Type
Monoclonal Mouse IgG1
Clone
9E239
Reactivity
Human
Verified Activity
1. Immunochemical staining of human HSPA1A in human hepatoma with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of human HSPA1A in human prostatic carcinoma with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:50-1:200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human HSP70 / HSPA1A (rh HSP70 / HSPA1A; TMPY-02443; NP_005337.2; Ala2-Asp641). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundHSPA1A is a member of the Hsp70 protein family. The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. HSP are abundant and conserved proteins present in all cells. Upon temperature shock or other stress stimuli, HSP is synthesized intracellularly, which may protect cells from protein denaturation or death. Extracellularly, HSP can serve a cytokine function to initiate both innate and adaptive immunity through activation of APC. HSP serves also a chaperone function and facilitates the presentation of antigen peptide to T cells. Molecular chaperones of the Hsp70 family have diverse functions in cells. They assist the folding of newly synthesized and stress-denatured proteins, as well as the import of proteins into organelles, and the dissociation of aggregated proteins. The well-conserved Hsp70 chaperones are ATP dependent: binding and hydrolysis of ATP regulate their interactions with unfolded polypeptide substrates, and ATPase cycling is necessary for their function. All cellular functions of Hsp70 chaperones use the same mechanism of ATP-driven polypeptide binding and release.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human HSP70 / HSPA1A Protein (TMPY-02443)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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