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Synonyms: p-PPAR gamma/PPARG (Ser112), p-PPAR gamma/PPARG (S112), PPAR-gamma, PPARG, PPAR gamma/PPARG (p-Ser112), PPAR gamma/PPARG (p-S112), Peroxisome proliferator-activated receptor gamma, Nuclear receptor subfamily 1 group C member 3, NR1C3
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-Phospho-PPAR gamma/PPARG (Ser112) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PPAR gamma/PPARG (Ser112). Anti-Phospho-PPAR gamma/PPARG (Ser112) Polyclonal Antibody can be used in ELISA, FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | p-PPAR gamma/PPARG (Ser112), p-PPAR gamma/PPARG (S112), PPAR-gamma, PPARG, PPAR gamma/PPARG (p-Ser112), PPAR gamma/PPARG (p-S112), Peroxisome proliferator-activated receptor gamma, Nuclear receptor subfamily 1 group C member 3, NR1C3 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Rabbit,GuineaPig) |
| Application | |
| Recommended Dose | ELISA=1:5000-10000; FCM=1 μg/Test; ICC/IF=1:100-500; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nuclear |
| Tissue Specificity | Skeletal muscle, liver, heart and kidney. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthesised phosphopeptide: human PPAR Gamma around the phosphorylation site of ser112 |
| Antigen Species | Human |
| Gene Name | PPARG |
| Gene ID | |
| Protein Name | Peroxisome proliferator-activated receptor gamma |
| Uniprot ID | |
| Biology Area | Diabetes associated,Metabolism,Zinc Finger,Fatty acids,Fatty acid oxidation,Diabetes,Heart disease,Obesity,Metabolism,Adipogenesis |
| Function | Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. |
| Molecular Weight | Theoretical: 57 kDa. Actual: 57 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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