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Anti-c-Myc Polyclonal Antibody
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Catalog No. TMAB-00451
Alias bHLHe39
Anti-c-Myc Polyclonal Antibody is a Rabbit antibody targeting c-Myc. Anti-c-Myc Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-c-Myc Polyclonal Antibody
Anti-c-Myc Polyclonal Antibody
😃Good
Catalog No. TMAB-00451Alias bHLHe39
Anti-c-Myc Polyclonal Antibody is a Rabbit antibody targeting c-Myc. Anti-c-Myc Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-c-Myc Polyclonal Antibody is a Rabbit antibody targeting c-Myc. Anti-c-Myc Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Alias | bHLHe39 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Dog,Pig,Cow,Rabbit,Sheep) |
| Verified Activity | Tissue/cell: human gastric carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-C-Myc Polyclonal Antibody, Unconjugated (TMAB-00451) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus, nucleoplasm. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human C-Myc |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cell differentiation,Transcription factors,Oncoproteins,HLH / Leucine Zipper,Transcription Factors,c-myc,Nuclear |
| Molecular Weight | Theoretical: 49 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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