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Anti-c-Myc Polyclonal Antibody
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Catalog No. TMAB-00451
Alias bHLHe39
Anti-c-Myc Polyclonal Antibody is a Rabbit antibody targeting c-Myc. Anti-c-Myc Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-c-Myc Polyclonal Antibody
Anti-c-Myc Polyclonal Antibody
😃Good
Catalog No. TMAB-00451Alias bHLHe39
Anti-c-Myc Polyclonal Antibody is a Rabbit antibody targeting c-Myc. Anti-c-Myc Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $372 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-c-Myc Polyclonal Antibody is a Rabbit antibody targeting c-Myc. Anti-c-Myc Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | bHLHe39 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Dog,Pig,Cow,Rabbit,Sheep) |
| Verified Activity | Tissue/cell: human gastric carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-C-Myc Polyclonal Antibody, Unconjugated (TMAB-00451) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining  |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus, nucleoplasm. |
| Tissue Specificity | Low levels detected throughout embryo before cellular blastoderm formation, particularly concentrated in pole plasm. Zygotic expression detected during cellular blastoderm stage in endodermal anlagen of anterior and posterior midgut at both poles. After g |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human C-Myc |
| Antigen Species | Human |
| Gene Name | MYC |
| Gene ID | |
| Protein Name | Myc proto-oncogene protein |
| Uniprot ID | |
| Biology Area | Cell differentiation,Transcription factors,Oncoproteins,HLH / Leucine Zipper,Transcription Factors,c-myc,Nuclear |
| Function | Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes. |
| Molecular Weight | Theoretical: 49 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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