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Anti-c-Myc Polyclonal Antibody

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Catalog No. TMAB-00451

Anti-c-Myc Polyclonal Antibody is a Rabbit antibody targeting c-Myc. Anti-c-Myc Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-c-Myc Polyclonal Antibody

Anti-c-Myc Polyclonal Antibody

😃Good
Catalog No. TMAB-00451
Anti-c-Myc Polyclonal Antibody is a Rabbit antibody targeting c-Myc. Anti-c-Myc Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceAvailabilityQuantity
50 μL$220 7-10 days
100 μL$372 7-10 days
200 μL$527 7-10 days
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Product Introduction

Bioactivity
Description
Anti-c-Myc Polyclonal Antibody is a Rabbit antibody targeting c-Myc. Anti-c-Myc Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Dog,Pig,Cow,Rabbit,Sheep)
Verified Activity
Tissue/cell: human gastric carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-C-Myc Polyclonal Antibody, Unconjugated (TMAB-00451) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining
Application
IHC-P,IHC-Fr,IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus, nucleoplasm.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThe protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human C-Myc
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Cell differentiation,Transcription factors,Oncoproteins,HLH / Leucine Zipper,Transcription Factors,c-myc,Nuclear
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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