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OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi)

Catalog No. TMPK-00463
Synonyms: CD134, OX40 homologue, OX40, IMD16, OX40L receptor,  TXGP1L, TNFRSF4, Ly-70, ACT-135

Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.

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OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 324.00
500 μg 5 days $ 1,300.00
1 mg 5 days $ 2,170.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.
Species Mouse
Expression System HEK293
Tag C-His-Avi
Accession Number P47741
Synonyms CD134, OX40 homologue, OX40, IMD16, OX40L receptor,  TXGP1L, TNFRSF4, Ly-70, ACT-135
Construction Recombinant Mouse OX40/TNFRSF4/CD134 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Val20-Pro211.[Accession |P47741]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 92% as determined by HPLC
Molecular Weight The protein has a predicted MW of 24.2 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per ug by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.

References and Literature

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Keywords

OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi) CD134 OX40 homologue OX-40 OX40 ACT 135 ACT135 TNFRSF 4 TNFRSF-4 IMD16 CD 134 OX40L receptor  TXGP1L TXGP1L IMD 16 TNFRSF4 IMD-16 OX 40 CD-134 Ly-70 ACT-135 recombinant recombinant-proteins proteins protein

 

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