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Anti-Arp3/ACTR3 Antibody (2D811)
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Catalog No. TMAH-00021
Alias ARP3 actin-related protein 3 homolog (yeast), ARP3
Anti-Arp3/ACTR3 Antibody (2D811) is an antibody targeting Arp3/ACTR3. Anti-Arp3/ACTR3 Antibody (2D811) can be used in ELISA, WB.
Anti-Arp3/ACTR3 Antibody (2D811)
Anti-Arp3/ACTR3 Antibody (2D811)
😃Good
Catalog No. TMAH-00021Alias ARP3 actin-related protein 3 homolog (yeast), ARP3
Anti-Arp3/ACTR3 Antibody (2D811) is an antibody targeting Arp3/ACTR3. Anti-Arp3/ACTR3 Antibody (2D811) can be used in ELISA, WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $208 | 7-10 days | |
| 100 μL | $347 | 7-10 days |
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Arp3/ACTR3 Antibody (2D811) is an antibody targeting Arp3/ACTR3. Anti-Arp3/ACTR3 Antibody (2D811) can be used in ELISA, WB. |
| Alias | ARP3 actin-related protein 3 homolog (yeast), ARP3 |
| Ig Type | Rabbit IgG |
| Clone | 2D811 |
| Reactivity | Human, Mouse, Rat |
| Verified Activity | Western Blot -Positive WB detected in: PC-3 whole cell lysate, K562 whole cell lysate, HL-60 whole cell lysate, A549 whole cell lysate, Mouse Spleen whole cell lysate, Rat Spleen whole cell lysate -All lanes: Arp3 Antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 48 kDa -Observed band size: 48 kDa |
| Application | ELISA, WB |
| Recommended Dose | WB:1:500-1:5000. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm, cytoskeleton. Cell projection. Nucleus. Note=In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes) (PubMed:19109554). |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. In podocytes, required for the formation of lamellipodia downstream of AVIL and PLCE1 regulation. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs). Plays a role in ciliogenesis. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human Arp3 |
| Antigen Species | Human |
| Gene ID | 10096 |
| Uniprot ID | |
| Biology Area | Tags & Cell Markers, Immunology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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