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Anti-LAG-3 Antibody-PE (6Z541)

(Synonyms: lymphocyte-activation gene 3, LAG-3, CD223) Copy Product Info
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Synonyms: lymphocyte-activation gene 3, LAG-3, CD223

Catalog No. TMAY-02828P Copy Product Info
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Anti-LAG-3 Antibody-PE (6Z541) is a PE-conjugated Mouse antibody targeting LAG-3. Anti-LAG-3 Antibody-PE (6Z541) can be used in FCM.
Anti-LAG-3 Antibody-PE (6Z541)
Pack SizePriceUSA StockGlobal StockQuantity
25 T$817-10 days7-10 days
100 T$1757-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-LAG-3 Antibody-PE (6Z541) is a PE-conjugated Mouse antibody targeting LAG-3. Anti-LAG-3 Antibody-PE (6Z541) can be used in FCM.
Synonymslymphocyte-activation gene 3, LAG-3, CD223
Ig Type
Mouse IgG1
Clone
6Z541
Reactivity
Human
Specificity
Human LAG-3
Application
Recommended Dose
5 μL/Test, 0.1 mg/mL
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis product is a recombinant monoclonal antibody expressed from HEK293 cells, and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundLAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling, leading to increased antigen-specific T-cell responses in vivo. Diseases associated with LAG3 include Smoldering Myeloma and Kyphoscoliotic Heart Disease.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
PE
Antigen Details
Immunogen
Recombinant Protein: Human LAG3 Protein
Antigen Species
Human
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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