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Anti-LAG-3 Antibody-PE (6Z541)

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Catalog No. TMAY-02828P

Anti-LAG-3 Antibody-PE (6Z541) is a PE-conjugated Mouse antibody targeting LAG-3. Anti-LAG-3 Antibody-PE (6Z541) can be used in FCM.

Anti-LAG-3 Antibody-PE (6Z541)

Anti-LAG-3 Antibody-PE (6Z541)

🥰Excellent
Catalog No. TMAY-02828P
Anti-LAG-3 Antibody-PE (6Z541) is a PE-conjugated Mouse antibody targeting LAG-3. Anti-LAG-3 Antibody-PE (6Z541) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-LAG-3 Antibody-PE (6Z541) is a PE-conjugated Mouse antibody targeting LAG-3. Anti-LAG-3 Antibody-PE (6Z541) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
Clone
6Z541
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human LAG3 expression on human peripheral blood lymphocytes. Human peripheral blood mononulcear cells were stimulated for 72 hours with CD3 and CD28, then stained with PE-conjugated anti-Human LAG3. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Application
FCM
Recommended Dose
5 μL/Test, 0.1 mg/mL
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis product is a recombinant monoclonal antibody expressed from HEK293 cells, and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundLAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfamily. The LAG3 gene contains 8 exons. It is selectively expressed in activated T and NK cells. LAG3 contains 4 extracellular Ig-like domains and has a negative regulatory function in T cells. It also acts as a new marker of T cell-induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling, leading to increased antigen-specific T-cell responses in vivo. Diseases associated with LAG3 include Smoldering Myeloma and Kyphoscoliotic Heart Disease.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint TargetsImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
PE
Antigen Details
Immunogen
Recombinant Human LAG3 Protein
Antigen Species
Human
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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