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Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein

(Synonyms: Protein N, Nucleoprotein, Nucleocapsid protein) Copy Product Info

Synonyms: Protein N, Nucleoprotein, Nucleocapsid protein

Catalog No. TMPH-02392 Copy Product Info
Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein is expressed in E. coli expression system. The predicted molecular weight is 63.0 kDa and the accession number is P13699.
Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$18520 days20 days
10 µg$29720 days20 days
20 µg$51520 days20 days
50 µg$71320 days20 days
100 µg$91620 days20 days
200 µg$1,26020 days20 days
500 µg$1,93020 days20 days
1 mg$2,69020 days20 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein is expressed in E. coli expression system. The predicted molecular weight is 63.0 kDa and the accession number is P13699.
Species
LASV
Expression System
E. coli
TagTag Free
Accession NumberP13699
Amino AcidMSASKEIKSFLWTQSLRRELSGYCSNIKLQVVKDAQALLHGLDFSEVSNVQRLMRKERRDDNDLKRLRDLNQAVNNLVELKSTQQKSILRVGTLTSDDLLILAADLEKLKSKVIRTERPLSAGVYMGNLSSQQLDQRRALLNMIGMSGGNQGARAGRDGVVRVWDVKNAELLNNQFGTMPSLTLACLTKQGQVDLNDAVQALTDLGLIYTAKYPNTSDLDRLTQSHPILNMIDTKKSSLNISGYNFSLGAAVKAGACMLDGGNMLETIKVSPQTMDGILKSILKVKKALGMFISDTPGERNPYENILYKICLSGDGWPYIASRTSITGRAWENTVVDLESDGKPQKADSNNSSKSLQSAGFTAGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIHFFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQGSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGVVVEKKKRGGKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRTSTPRVVL
Construction1-569 aa
Protein Purity
> 85% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsProtein N, Nucleoprotein, Nucleocapsid protein
Research Background
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
Chemical Properties
Molecular Weight63.0 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein chemical structure | Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein molecular weight