Anti-CD133/PROM1 Polyclonal Antibody

Name: Anti-CD133/PROM1 Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-00332
Rating: 4.5 (1 reviews)

(Synonyms: PROML1, Prominin-like protein 1, Prominin-1, PROM1, CD133, Antigen AC133) Copy Product Info

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Synonyms: PROML1, Prominin-like protein 1, Prominin-1, PROM1, CD133, Antigen AC133

Catalog No. TMAB-00332 Copy Product Info

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Anti-CD133/PROM1 Polyclonal Antibody is a Rabbit antibody targeting CD133/PROM1. Anti-CD133/PROM1 Polyclonal Antibody can be used in FCM,WB.

Anti-CD133/PROM1 Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$222	7-10 days	7-10 days
100 μL	$374	7-10 days	7-10 days
200 μL	$528	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-CD133/PROM1 Polyclonal Antibody is a Rabbit antibody targeting CD133/PROM1. Anti-CD133/PROM1 Polyclonal Antibody can be used in FCM,WB.
Synonyms	PROML1, Prominin-like protein 1, Prominin-1, PROM1, CD133, Antigen AC133
Ig Type	IgG
Reactivity	Human,Mouse (predicted:Rat,Fruit Fly)

Application	FCM WB
Recommended Dose	WB: 1:500-2000; FCM: 1μg/Test
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Cell projection, cilium, photoreceptor outer segment. Isoform 1: Apical cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Note=Found in extracellular membrane particles in various body fluids such as cerebrospinal fluid, saliva, seminal fluid and urine.
Tissue Specificity	Isoform 1 is selectively expressed on CD34 hematopoietic stem and progenitor cells in adult and fetal bone marrow, fetal liver, cord blood and adult peripheral blood. Isoform 1 is not detected on other blood cells. Isoform 1 is also expressed in a number
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human CD133
Antigen Species	Human
Gene Name	PROM1
Gene ID	8842
Protein Name	Prominin-1
Uniprot ID	O43490
Biology Area	Neural Stem Cell marker,Surface Molecules,Surface Molecules
Function	Binds cholesterol in cholesterol-containing plasma membrane microdomains. Proposed to play a role in apical plasma membrane organization of epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.