Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Phospho-ATR (Ser428) Polyclonal Antibody

😃Good
Catalog No. TMAC-00343
Alias protein kinase ATR, kinase ATR, FRP1, FRAP-related protein, EC 2.7.11.1, ataxia telangiectasia and Rad3-related protein

Anti-Phospho-ATR (Ser428) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ATR (Ser428). Anti-Phospho-ATR (Ser428) Polyclonal Antibody can be used in IHC,IF.

Anti-Phospho-ATR (Ser428) Polyclonal Antibody

Anti-Phospho-ATR (Ser428) Polyclonal Antibody

😃Good
Catalog No. TMAC-00343Alias protein kinase ATR, kinase ATR, FRP1, FRAP-related protein, EC 2.7.11.1, ataxia telangiectasia and Rad3-related protein
Anti-Phospho-ATR (Ser428) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ATR (Ser428). Anti-Phospho-ATR (Ser428) Polyclonal Antibody can be used in IHC,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3187-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-Phospho-ATR (Ser428) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ATR (Ser428). Anti-Phospho-ATR (Ser428) Polyclonal Antibody can be used in IHC,IF.
Aliasprotein kinase ATR, kinase ATR, FRP1, FRAP-related protein, EC 2.7.11.1, ataxia telangiectasia and Rad3-related protein
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
IHC: 1:100-300; IF: 1:50-200
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research BackgroundSerine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates BRCA1, CHEK1, MCM2, RAD17, RPA2, SMC1 and p53/TP53, which collectively inhibit DNA replication and mitosis and promote DNA repair, recombination and apoptosis. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at sites of DNA damage, thereby regulating DNA damage response mechanism. Required for FANCD2 ubiquitination. Critical for maintenance of fragile site stability and efficient regulation of centrosome duplication.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human ATR around the phosphorylation site of Ser428
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-Phospho-ATR (Ser428) Polyclonal Antibody | purchase Anti-Phospho-ATR (Ser428) Polyclonal Antibody | Anti-Phospho-ATR (Ser428) Polyclonal Antibody cost | order Anti-Phospho-ATR (Ser428) Polyclonal Antibody