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Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody
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Catalog No. TMAC-00942
Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cortactin (Tyr466). Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody can be used in WB.
Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody
Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody
😃Good
Catalog No. TMAC-00942
Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cortactin (Tyr466). Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $216 | 7-10 days | |
| 100 μL | $316 | 7-10 days |
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| Description | Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cortactin (Tyr466). Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Cortactin is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 466 (P-V-Y(p)-E-T) derived from Human CORTACTIN |
| Antigen Species | human |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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