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Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody (Synonyms: p-Cortactin (Y466), p-Cortactin (Tyr466), Corta...)
Catalog No. TMAC-00942 Copy Product Info
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Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cortactin (Tyr466). Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody can be used in WB.
Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAC-00942
Synonyms p-Cortactin (Y466), p-Cortactin (Tyr466), Cortactin (p-Y466), Cortactin (p-Tyr466)
Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cortactin (Tyr466). Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody can be used in WB.
Anti-Phospho-Cortactin
(Tyr466) Polyclonal Antibody
(Tyr466) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $216 | 7-10 days | 7-10 days | |
| 100 μL | $316 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Cortactin (Tyr466). Anti-Phospho-Cortactin (Tyr466) Polyclonal Antibody can be used in WB. |
| Synonyms | p-Cortactin (Y466), p-Cortactin (Tyr466), Cortactin (p-Y466), Cortactin (p-Tyr466) |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of extracts from Jurkat cells untreated or treated with H2O2 using Cortactin (Phospho-Tyr466) Antibody TMAC-00942. 2. Western blot analysis of extracts from JK cells, treated with H2O2 or calf intestinal phosphatase (CIP), using Cortactin (Phospho-Tyr466) Antibody TMAC-00942.   |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Cortactin is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 466 (P-V-Y(p)-E-T) derived from Human CORTACTIN |
| Antigen Species | human |
| Uniprot ID |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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