Fas Ligand Protein, Human, Recombinant (His)

Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

Pack Size	Availability	Price/USD
50 μg	In stock	$ 335.00
100 μg	5 days	$ 523.00
200 μg	5 days	$ 814.00
500 μg	5 days	$ 1,460.00

Pack Size

Availability

Price/USD

Quantity

50 μg

In stock

$ 335.00

100 μg

5 days

$ 523.00

200 μg

5 days

$ 814.00

500 μg

5 days

$ 1,460.00

Biological Information

Immobilized Human Fas/CD95 hFc at 2 μg/mL (100 μL/well) can bind Human Fas Ligand His , the EC50 of Human Fas Ligand His is 40-200 ng/mL.

Description

Species	Human
Expression System	Yeast
Tag	His
Accession Number	P48023-1
Synonyms	TNLG1A, FASL, FASLG, CD178, CD95-L, APT1LG1, APTL, CD95L, Fas ligand, ALPS1B, TNFSF6
Construction	A DNA sequence encoding human FASLG (NP_000630.1) (Pro134-Leu281) was expressed with a polyhistidine tag at the N-terminus.
Protein Purity	> 90 % as determined by SDS-PAGE
Molecular Weight	Approxiamtely 19.3 kDa

Endotoxin	Please contact us for more information.
Formulation	Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution	A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage	Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.