Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
TargetMol | Compound Library

Anti-COVID-19 Compound Library

Catalog No. L1710

In response to the outbreak of COVID-19 caused by a novel coronavirus SARS-CoV-2, global scientific research institutions and pharmaceutical companies are stepping up related vaccine development and antiviral drug trials. Scientists from multiple countries are working hard to identify drug candidates that can be used for clinical therapy to patients with COVID-19 by screening compound libraries. TargetMol as a drug screening expert quickly generated this compound library to support the research and development of anti-COVID-19 drugs. This compound library includes Part1 and Part2. Part1 contains compounds that have been demonstrated to have anti-coronavirus activity or are broad-spectrum antiviral agents including Remdesivir, Lopinavir/Ritonavir, Chloroquine diphosphate (combination use with Remdesivir), Polydatin (bind with Mpro), etc. Part2 collects compounds from virtual screening hits based on molecular docking. These compounds with high-affinity to 7 SARS-CoV-2 protein targets (RBD of Spike protein, viral papain like protease (PLpro), main protease (3CLpro, also named 3-chymotrypsin-like protease), RNA-dependent RNA polymerase (RdRp), nsp16 (2′-O-methyltransferase, helicase), nsp15, and X-domain.) and 1 human ACE2 have the potential to provide more drug candidates for molecular and cellular antiviral activity assays. As a world-renowned supplier of small molecular compounds, TargetMol immediately after the outbreak of COVID-19 performed a Swiss-Model Homology Modelling process to generate reliable protein models or 3D protein structures of these related drug targets. Then structure-based virtual screening was performed against TargetMol libraries by using Surflex-Dock in the Sybyl-X 2.0 package. Having anti-COVID-19 CADD activity from virtual screening formed Part2 of this compound library. We wish these compounds would speed up the development of COVID-19 targeted drugs. We also will keep updating it in response to the newest research progress.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Resource Download
Library compound info
Excel
SDF
Contact us for more batch information

Catalog No. L1710

Anti-COVID-19 Compound Library

sizeIn stock

  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
Inquiry & Custom

Top Publication Citing
Use of TargetMol Products

Cite scientific literature on TargetMol products

View More

Product Description Product Description

  • A unique collection of 1133 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents;
  • Compounds contain Remdesivir, Lopinavir/Ritonavir, Chloroquine diphosphate (combination use with Remdesivir), Polydatin (bind with Mpro), etc.;
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Sci Citations

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
Inquiry & Custom

Library Customization | TargetMol Library Composition

Autophagy
Endogenous Metabolite
Apoptosis
Antibacterial
HIV Protease
Antibiotic
DNA/RNA Synthesis
Influenza Virus
SARS-CoV
HCV Protease
Parasite
Reactive Oxygen Species
Reverse Transcriptase
HBV
Potassium Channel
Adrenergic Receptor
Calcium Channel
5-HT Receptor
Antifungal
HSV
RAAS
COX
NF-κB
Cytochromes P450
Ferroptosis
Antioxidant
PI3K
AChR
Histamine Receptor
Nucleoside Antimetabolite/Analog
Mitophagy
VEGFR
Antiviral
Dopamine Receptor
Histone Methyltransferase
Dehydrogenase
Virus Protease
PDE
Prostaglandin Receptor
CCR
Epigenetic Reader Domain
Sodium Channel
Antifection
c-Kit
EGFR
PKC
TNF
Topoisomerase
FLT
HDAC
PDGFR
CDK
Phosphatase
PPAR
Proteasome
TLR
Akt
JAK
mTOR
ribosome
Adenosine Receptor
AMPK
Caspase
Src
c-Met/HGFR
Estrogen Receptor/ERR
FGFR
Raf
STAT
Bcl-2 Family
HMG-CoA Reductase
Integrin
MMP
Opioid Receptor
Phospholipase
Transferase
Tyrosine Kinases
Wnt/beta-catenin
Antifolate
ATPase
Bcr-Abl
Cholinesterase (ChE)
DHFR
ERK
Estrogen/progestogen Receptor
FAAH
GABA Receptor
Glucocorticoid Receptor
GSK-3
HIF/HIF Prolyl-Hydroxylase
Interleukin
MEK
P2Y Receptor
p38 MAPK
PROTACs
Ras
TAM Receptor
TGF-beta/Smad
Cannabinoid Receptor
Carbonic Anhydrase
c-RET
Drug Metabolite
Gamma-secretase
HSP
iGluR
Microtubule Associated
MRP
Nrf2
Reductase
Sirtuin
Thrombin
TRP/TRPV Channel
Tyrosinase
Beta Amyloid
c-Fms
CXCR
Cysteine Protease
DNA
DNA-PK
E1/E2/E3 Enzyme
Fatty Acid Synthase
GluCls
Glucosidase
GPR
IGF-1R
IRAK
JNK
Lipoxygenase
MAO
Mitochondrial Metabolism
NADPH
NMDAR
NO Synthase
Norepinephrine
NOS
P-gp
PKA
Rho
ROS
Serine Protease
Serine/threonin kinase
ADC Linker
Acetyl-CoA Carboxylase
Amino Acids and Derivatives
Androgen Receptor
ATM/ATR
CaMK
Casein Kinase
CaSR
Chk
CRISPR/Cas9
CSF-1R
DNA Methyltransferase
DPP-4
FAK
Gap Junction Protein
Glucokinase
GluR
HER
HIF
Histone Acetyltransferase
Hydroxylase
IL Receptor
IκB/IKK
Kinesin
Ligand for E3 Ligase
Lipase
LPL Receptor
Lysosomal Autophagy
MicroRNA
NAMPT
NOD-like Receptor (NLR)
OX Receptor
P2X Receptor
p53
PAI-1
PARP
PD-1/PD-L1
PDK
Platelet aggregation
PLK
Protease-activated Receptor
Proton pump
PTEN
RSV
S1P Receptor
S6 Kinase
Serotonin Transporter
SGLT
Telomerase
transporter
Trk receptor
ABC Transporter
ACK1
Acyltransferase
Adiponectin Receptor
AhR
ALK
Aminopeptidase
Annexin A
Aromatase
ASK
ATP Citrate Lyase
Aurora Kinase
Bombesin Receptor
Bradykinin Receptor
cAMP
Cell Cycle Arrest
Cell wall
CETP
CFTR
Chloride channel
Cholecystokinin Receptor
Complement System
CRM1
Decarboxylase
Discoidin Domain Receptor (DDR)
DNA gyrase
Endothelin Receptor
Fas/FasL
FXR
Glutaminase
Glutathione Peroxidase
Glutathione reductase
GNRH Receptor
gp120/CD4
GPCR19
GST
GTPase
Guanylate cyclase
Hck
Hedgehog/Smoothened
IAP
IFNAR
Integrase
IRE1
LDL
Ligands for Target Protein for PROTAC
Lipid
LPA Receptor
MAPK
Mdm2
Melatonin Receptor
MLK
MNK
Molecular Glues
MT Receptor
Na+/Ca2+ Exchanger
NADPH-oxidase
NEDD8
Neprilysin
Neurokinin receptor
NPC1L1
OAT
PAK
PERK
PGE Synthase
Phosphorylase
PI4K
PROTAC Linker
Pyroptosis
RAR/RXR
Retinoid Receptor
ROR
Sigma receptor
Stearoyl-CoA Desaturase (SCD)
Stemness kinase
Survivin
Syk
Taste receptor
Thioredoxin
Thyroid hormone receptor(THR)
Tie-2
TOPK
UGT
Vasopressin Receptor
VDA
YAP
ADC Cytotoxin
BTK
PGC-1α

Keywords