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Anti-Phospho-MKP-1 (Ser359) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MKP-1 (Ser359). Anti-Phospho-MKP-1 (Ser359) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $216 | 7-10 days | |
100 μL | $316 | 7-10 days |
Description | Anti-Phospho-MKP-1 (Ser359) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MKP-1 (Ser359). Anti-Phospho-MKP-1 (Ser359) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),ELISA. |
Ig Type | IgG |
Reactivity | Human |
Application | |
Recommended Dose | IHC-P: 1:100-300; ELISA: 1:10000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | dual specificity phosphatase 1(DUSP1) Homo sapiens The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferati |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human MKP1 around the phosphorylation site of Ser359. AA range:318-367 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Theoretical: 39 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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