SLITRK1 Protein, Human, Recombinant (His)

Name: SLITRK1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-00923
Price: 70 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: TTM, SLITRK1, SLIT and NTRK like family member 1, RP11-395N17.1, LRRC12, KIAA1910, KIAA0918, FLJ54428) Copy Product Info

Synonyms: TTM, SLITRK1, SLIT and NTRK like family member 1, RP11-395N17.1, LRRC12, KIAA1910, KIAA0918, FLJ54428

Catalog No. TMPY-00923 Copy Product Info

SLITRK1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 105-115 kDa and the accession number is Q96PX8.

Pack Size	Price	USA Stock	Global Stock
5 µg	$70	-	In Stock
10 µg	$109	-	In Stock
20 µg	$182	-	In Stock
50 µg	$357	-	In Stock
100 µg	$600	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	SLITRK1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 105-115 kDa and the accession number is Q96PX8.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q96PX8
Construction	A DNA sequence encoding the extracellular domain (Met 1-Ser 616) of human SLITRK1 (NP_443142.1) was expressed with a C-terminal polyhistidine tag. Predicted N terminal: Asn 18
Protein Purity	> 95 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	TTM, SLITRK1, SLIT and NTRK like family member 1, RP11-395N17.1, LRRC12, KIAA1910, KIAA0918, FLJ54428
Research Background	SLITRK1 (Slit and Trk-like family member 1) is a integral membrane protein belonging to the SLITRK family consists of at least 6 members (SLITRK1-6). They are named and characterized by the presence of two leucine-rich repeats (LRRs) in the extracellular domain similar to those found in a secreted axonal growth-controlling protein, Slit, as well as a C-terminal domain with homology to Trk neurotrophin tyrosine kinase receptors. Expression of SLITRKs are highly restricted to neural tissues, and are identified as the neuronal components modulating the neurite outgrowth. More specifically, SLITRK1 expression is found in the mature neurons of the cerebrum, thalamus and hippocampus, and induces unipolar neurites in cultured neuronal cells. Human SLITRK1 is a 696 amino acid precursor protein, and one truncating frameshift mutation (448 aa) has been linked to Tourette's syndrome, a genetically influenced developmental neuropsychiatric disorder characterized by chronic vocal and motor tics. In addition, all SLITRK genes are differentially expressed in brain tumors, such as astrocytoma, oligodendroglioma, glioblastoma, and are suggested to be useful molecular indicators of brain tumor properties.

Chemical Properties

Molecular Weight

81.2 kDa (predicted); 105-115 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.