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Antiviral

Antiviral drugs are a class of medication used specifically for treating viral infections rather than bacterial ones. Most antivirals are used for specific viral infections, while a broad-spectrum antiviral is effective against a wide range of viruses.

  • Hypericin
    T6S0923548-04-9
    1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL-mediated osteoclastogenesis via affecting ERK signalling in vitro and suppresses wear particle-induced osteolysis in vivo.
    • $52
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  • SIRT1-IN-1
    T9648352554-02-0In house
    SIRT1-IN-1 is a selective inhibitor of SIRT1 with an IC50 of 205 nM. SIRT1-IN-1 is an inhibitor of cytomegalovirus (CMV) with antiviral activity.
    • $97
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  • Rociclovir PM
    T6780789419-23-8In house
    Rociclovir PM (2-[(2-aminopurin-9-yl)methoxy]propane-1,3-diol) is a compound with antiviral activity
    • $197
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  • Braco-19
    T26892351351-75-2
    Braco-19 is a telomerase/telomere inhibitor and an inhibitor of HAdV viral replication with antiviral activity that reduces lipid vacuolization in adipocytes, inhibits proliferation and decreases telomerase activity in human glioblastoma cells.
    • $48
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  • Paederoside
    T3S087220547-45-9
    1. Paederoside is a potent deterrent against the beetle was isolated from the aphid . 2. Paederoside displays high anti-tumor promoting activity against the Epstein-Barr virus activation.
    • $130
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  • BTA-188
    T67792314062-80-1In house
    BTA-188 is one of the most potent analogues of novel and orally active synthetic benzoxazole and benzothiazole derivatives with significant anti-rhinovirus activity.
    • $197
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  • Peramivir
    T21339330600-85-6
    Peramivir (BCX1812) is a highly selective influenza A and B neuraminidase inhibitor with antiviral activity and anti-cytokine effects, which can be used in the study of novel coronavirus and influenza virus infections.
    • $30
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  • Tyrosine kinase-IN-7
    T77746345615-74-9
    Tyrosine kinase-IN-7 is a potent inhibitor of the tyrosine kinase EGFR, inhibiting EGFR(WT) and EGFR(T790M) and showing anti-cancer and anti-tumor activity in a variety of cancer cell lines. Tyrosine kinase-IN-7 has potential anti-inflammatory and antiviral activities.
    • $30
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  • β-Anomer
    TNU0422356782-84-8In house
    β-Anomer shows antiviral properties.
    • $30
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  • Somantadine
    T987479594-24-4In house
    Somantadine has antiviral activities and can be used for research on preventing and treating coronavirus-related diseases.
    • $50
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  • Epetirimod
    T31648227318-71-0In house
    Epetirimod (S-30563) is a small molecule immunomodulator with antitumor and anti-infective activity for the study of papillomavirus infections.
    • $210 TargetMol
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  • IND24
    T255311426047-44-0
    IND24 has anti-prion activity and can be used to study neurodegenerative diseases.
    • $195
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  • Rociclovir
    T67806108436-80-2In house
    Rociclovir has antiviral activity and is used to treat viral infections.
    • $192
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  • 2’-beta-C-Methyl inosine
    TNU0442374750-32-0
    2’-beta-C-Methyl inosine (2’-C-Methylinosine) is an HCV RNA polymerase inhibitor with antiviral activity and is being studied for the treatment of hepatitis C virus infection.
    • $173
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  • LCC-12 FA
    T83971L3029253-76-4
    LCC-12 FA is a dimer composed of metformin that induces a decrease in the NAD(H) pool by targeting mitochondrial copper(ii).LCC-12 FA reduces inflammation in mouse models of bacterial and viral infections and may be used in the study of metabolic diseases.
    • $195
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  • 5-Hydroxy-7-acetoxy-8-methoxyflavone
    TN312095480-80-1
    5-Hydroxy-7-acetoxy-8-methoxyflavone is a flavonoid compound that inhibits lipid peroxidation and may have anti-influenza virus activity.
    • $248
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  • IM-250
    T806752305750-23-4
    IM-250 Possesses antiviral activity with IC values of 25 nM - 100 nM.
    • $313
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  • IQP-0528
    T27625301297-45-0In house
    IQP-0528 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) that has potential for the treatment of HIV infection by blocking viral entry and shows antiviral activity as a microbicidal gel. . IQP-0528 showed inhibition of both HIV-1 and HIV-2, with an EC50 of 0.2 nM for HIV-1 and 100 nM for HIV-2.
    • $113
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  • Antiviral agent 17
    T60440158227-81-7
    Antiviral agent 17 is a nucleoside analog with antiviral and antiparasitic activity, inhibits hepatitis C virus 1B and inhibits Trypanosoma brucei and Trypanosoma brucei, and can be used in the study of viral infections and malignant diseases.
    • $30
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  • ABI-1968
    T677851626364-18-8In house
    ABI-1968 has antiviral and antitumor activity and can be used to study immune system diseases.
    • $970
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  • Oxamisole TFA
    T33836L In house
    Oxamisole TFA is an orally available T-cell immune repair agent.
    • $176
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  • Bonafton
    T88776954-48-9
    Bonafton (Bonaphthone) is an antiviral agent.
    • $67
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  • Antiviral agent 34
    T77632945152-88-5
    Antiviral agent 34 is an orally available, potent antiviral compound that inhibits influenza A and B viruses.Antiviral agent 34 inhibits the proliferation of influenza viruses by modulating RNA polymerase.Antiviral agent 34 is used in the study of viral infections.
    • $195
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  • 2-PADQZ hydrochloride
    T19849L84050-22-6
    2-PADQZ hydrochloride shows antiviral activity and targets influenza A virus RNA promoter.
    • $195
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  • R 61837
    T26020100241-46-1In house
    R 61837 is a novel rhinovirus inhibitor, a substituted phenylpyridazinamine, with antiviral activity.
    • $293 TargetMol
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  • DDG-39
    T67797119555-47-4In house
    DDG-39 (1-(2,3-dideoxy-2-fluoropentofuranosyl)cytosine) possesses antiviral activity with potent and selective anti-HIV-1 and HBV activity in cell culture. The average antiviral IC50 is 0.61 μM.
    • $189
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  • GS-9191 PM
    T67821 In house
    GS-9191 PM is a novel antitumorviral compound, a bis-amide prodrug of the nucleotide analog 9-(2-phosphonomethoxyethyl)-N6-cyclopropyl-2,6-diaminopurine (cPrPMEDAP).GS-9191 PM is a potent inhibitor of MDR1 and BCRP.GS-9191 PM exhibits both antiproliferative and antitumorviral activities.
    • $138
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  • AMC-01
    T299551047978-71-1In house
    AMC-01 has potential antiviral activity and induces dose- and time-dependent inactivation of eIF2-α via phosphorylation of serine residue 51. AMC-01 can be used to study atherosclerosis and Parkinson's syndrome.
    • $350
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  • GPS491
    T402932655502-29-5In house
    GPS491 has antiviral activity and inhibits HIV-1, adenovirus, and coronavirus replication by altering RNA processing.
    • $350
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  • H-Lys-Trp-Lys-OH acetate
    T15457L
    H-Lys-Trp-Lys-OH acetate is a peptide with antibacterial and antiviral activities.
    • $50
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  • Viroxime
    T31644L63198-97-0In house
    Viroxime has antiviral activity and may be used to study coxsackievirus infection in infants.
    • $129 TargetMol
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  • Tirilazad mesylate
    T28978110101-67-2In house
    Tirilazad mesylate (U 74006F) is a non-glucocorticoid, lipid peroxidation inhibitor with antiviral activity and neuroprotective activity.Tirilazad mesylate confines intracellular intramembranous foci, attenuates spinal cord injury induced by trauma, stroke, and ischemia/reperfusion injuries, inhibits toxins in dogs, reduces the effects of Tirilazad mesylate is used in the study of neurological disorders.
    • $579
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  • DNA polymerase-IN-1
    T80644809234-33-1In house
    DNA polymerase-IN-1, a DNA polymerase inhibitor, exhibited antiproliferative activity against tumor cells with a half-inhibitory concentration (IC50) of 20.7 μM. DNA polymerase-IN-1 inhibited Taq DNA polymerase with an IC50 of less than 250 μM. DNA polymerase-IN-1 was shown to inhibit Taq DNA polymerase by RT- DNA polymerase-IN-1 showed antiretroviral activity in vitro by RT-PCR assay and can be used to study oxidative damage and colorectal cancer.
    • $195 TargetMol
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  • 3’-O-Methyladenosine
    TNU006010300-22-8
    3’-O-Methyladenosine is an antiviral compound with inhibitory activity against West Nile Virus and can be used for the treatment of viral infections.3’-O-Methyladenosine inhibits adenosine deaminase type VII with a Ki value of 493 µM.
    • $40
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  • Antiviral agent 38
    T643962247932-38-1In house
    2H-Pyrido[2',1':3,4]pyrazino[1,2-b]indazole-3-carboxylic acid, 6-(1, 1-Dimethylethyl)-6, 7-Dihydro-10 -(3-methoxypropoxy)-2-oxo-, (6R)- has antibacterial and antiviral activity and can be used to study Hepatitis B virus.
    • $195
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  • UC-781
    T29037178870-32-1In house
    UC-781 (NSC-675186) is a potent and selective inhibitor of human immunodeficiency virus HIV-1 non-nucleoside reverse transcriptase (NNRTI) I with a C50 value of 5 nM.UC-781 exhibits both antiviral activity and drug resistance.UC-781 is in a stable state, and is unaffected by lower pH or varying temperatures.
    • $191
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  • (R,1R)-Tenofovir amibufenamide
    T632901571076-37-3In house
    (R,1R)-Tenofovir amibufenamide ((R,1R)-HS-10234) can be used as a Tenofovir prodrug, which can be taken orally and has antiviral activity. Tynofovir is a nucleotide reverse transcriptase inhibitor.
    • $127
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  • BF738735
    T165301436383-95-7In house
    BF738735 is a selective inhibitor of phosphatidylinositol 4-kinase III beta (PI4KIIIβ, IC50 = 5.7 nM) showing higher activity over α(IC50 = 1.7 μM). BF738735 exhibits a broad spectrum of antiviral activity.
    • $40
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  • Azaribine
    T251302169-64-4In house
    Azaribine (2;,3;,5;-Tri-O-acetyl-6-azauridine) is an orotate monophosphate decarboxylase (OMPD) inhibitor with broad-spectrum antiviral activity, inhibiting viral genome replication and gene transcription.Azaribine has been used in the study of Zika virus (ZIKV) infections, and in the study of psoriasis, arthritis and mycosis fungoides. Azaribine is used to study Zika virus (ZIKV) infections, psoriasis and mycosis fungoides.
    • $40 TargetMol
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  • WIN 54954
    T61652107355-45-3In house
    WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and inhibits viral translation or transcription.WIN 54954 may be useful in the study of small ribonucleic acid virus infections.
    • $52 TargetMol
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  • CMP-5
    T10850880813-42-3In house
    CMP-5 is a PRMT5 inhibitor with antiviral activity, inhibits PRMT5 methyltransferase activity, and can be used in the study of SARS virus infection.
    • $39
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  • HBF-0259
    T27527957011-15-3In house
    HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells. HBF-0259 had a EC50 of approximately 1.5 microM in a secondary, HBV-expressing cell line, with a concentration that exhibited 50% cytotoxicity of >50 microM. The equilibrium concentration of HBF-0259 in aqueous solution at physiological pH was 15 to 16 microM; the selective index was thus >9.
    • $32
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  • Ezurpimtrostat hydrochloride
    T628821914148-73-4In house
    Ezurpimtrostat hydrochloride (GNS561 hydrochloride) is an orally available palmitoyl protein thioesterase-1 inhibitor with antifibrotic, antiviral, and anticancer effects that blocks cancer cell proliferation by interacting with palmitoyl protein thioesterase to inhibit late autophagy and dose-dependently increase lysosomal accumulation.
    • $148 TargetMol
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  • JNJ-49095397
    T729181220626-82-3In house
    JNJ-49095397 (RV568) is a selective p38 MAPK-α and p38 MAPK--γ kinase inhibitor with anti-inflammatory activity and potential antiviral activity for chronic obstructive pulmonary disease (COPD), cystic fibrosis, and respiratory syncytial virus infection.
    • $88
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  • CMX-521
    T699412077178-99-3
    CMX-521 has antiviral activity, inhibits oronavirus activity, and can be used in the study of viral infections.
    • $397 TargetMol
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  • (R)-JAK2/STAT3-IN-10a
    T72754L2485758-49-2
    (R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a GP130 D1 structural domain inhibitor with antitumor activity that inhibits the phosphorylation of JAK2 and STAT3. The KD value of (R)-JAK2/STAT3-IN-1 on GP130 protein is 3.8 μM.
    • $195 TargetMol
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  • Epigoitrin
    T5S00921072-93-1
    1. Epigoitrin (Goitrin) has anti-virus activity. 2. Epigoitrin has anti-oxidant activity. 3. Epigoitrin has anti-inflammation activity.
    • $31
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    TargetMol | Citations Cited
  • Angelicin
    T2875523-50-2
    Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.
    • $35
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  • Germacrone
    T29456902-91-6
    Germacrone is extracted from Curcuma zedoaria and has anti-inflammatory, anti-androgenic and antiviral activities. It also inhibits the proliferation of glioma cells by promoting apoptosis.
    • $41
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  • Brincidofovir
    TQ0095444805-28-1
    Brincidofovir (HDP-CDV) is an orally active, lipophilic form of cidofovir. It has enhanced activity compared to CDV against certain adenoviruses, herpesviruses, and orthopoxviruses.
    • $48
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