FGF-14 Protein, Canine, Recombinant

Name: FGF-14 Protein, Canine, Recombinant
Brand: TargetMol
SKU: TMPY-04033
Rating: 4.5 (1 reviews)

(Synonyms: fibroblast growth factor 14) Copy Product Info

Synonyms: fibroblast growth factor 14

Catalog No. TMPY-04033 Copy Product Info

FGF-14 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.1 kDa and the accession number is XP_003363267.1.

Pack Size	Price	USA Stock	Global Stock
5 µg	$87	7-10 days	7-10 days
10 µg	$142	7-10 days	7-10 days
20 µg	$233	7-10 days	7-10 days
50 µg	$535	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its binding ability in a functional ELISA. Immobilized Canine FGF14 at 2 μg/ml (100 μl/well) can bind Human FGFR4 hFc, the EC50 of Human FGFR4 hFc is 300-950 ng/mL.
Description	FGF-14 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 21.1 kDa and the accession number is XP_003363267.1.
Species	Canine
Expression System	E. coli
Tag	Tag Free
Accession Number	XP_003363267.1
Construction	A DNA sequence encoding the canine FGF14 (XP_003363267.1)(Lys64-Thr252)was expressed with a N-terminal Met. Predicted N terminal: Met
Protein Purity	> 95 % as determined by SDS-PAGE
Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	fibroblast growth factor 14
Research Background	FGF14 is a member of the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF14 is probably involved in nervous system development and function. Defects in FGF14 are the cause of spinocerebellar ataxia type 27 (SCA27). It is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA27 is an autosomal dominant cerebellar ataxia. It is a slowly progressive disorder, with onset in late-childhood to early adulthood, characterized by ataxia with tremor, orofacial dyskinesia, psychiatric symptoms and cognitive deficits.

Chemical Properties

Molecular Weight

21.1 kDa (predicted); 21 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.