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Anti-IL-27RA/TCCR Polyclonal Antibody
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Catalog No. TMAB-00958
Alias ZcytoR1, WSX-1, WSX1, TCCR, IL-27R-α, IL-27R-alpha, IL-27RA, IL27RA, IL27R α, IL27R alpha, IL-27 RA, IL27 RA, CRL1
Anti-IL-27RA/TCCR Polyclonal Antibody is a Rabbit antibody targeting IL-27RA/TCCR. Anti-IL-27RA/TCCR Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-IL-27RA/TCCR Polyclonal Antibody
Anti-IL-27RA/TCCR Polyclonal Antibody
😃Good
Catalog No. TMAB-00958Alias ZcytoR1, WSX-1, WSX1, TCCR, IL-27R-α, IL-27R-alpha, IL-27RA, IL27RA, IL27R α, IL27R alpha, IL-27 RA, IL27 RA, CRL1
Anti-IL-27RA/TCCR Polyclonal Antibody is a Rabbit antibody targeting IL-27RA/TCCR. Anti-IL-27RA/TCCR Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-IL-27RA/TCCR Polyclonal Antibody is a Rabbit antibody targeting IL-27RA/TCCR. Anti-IL-27RA/TCCR Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Synonyms | ZcytoR1, WSX-1, WSX1, TCCR, IL-27R-α, IL-27R-alpha, IL-27RA, IL27RA, IL27R α, IL27R alpha, IL-27 RA, IL27 RA, CRL1 |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Highly expressed in lymphoid tissues such as spleen, lymph nodes and peripheral blood leukocytes. Weakly expressed in other tissues examined including heart, brain, fetal and adult lung, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, s |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Upon antigen challenge, T-helper cells differentiate into two functionally distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-b that augment the cell-mediated immune response, while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominantly expressed in thymus, spleen, lymph nodes and peripheral blood leukocytes. |
| Immunogen | KLH conjugated synthetic peptide: human IL27RA |
| Antigen Species | Human |
| Gene Name | IL27RA |
| Gene ID | |
| Protein Name | Interleukin-27 receptor subunit alpha |
| Uniprot ID | |
| Biology Area | STATs,Interleukins,STATs |
| Function | Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms. |
| Molecular Weight | Theoretical: 70 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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