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Anti-IL-18 Polyclonal Antibody (Synonyms: interleukin 18, Il-18, Igif)
Catalog No. TMAB-00950 Copy Product Info
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Anti-IL-18 Polyclonal Antibody is a Rabbit antibody targeting IL-18. Anti-IL-18 Polyclonal Antibody can be used in WB.
Anti-IL-18 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-00950
Synonyms interleukin 18, Il-18, Igif
Anti-IL-18 Polyclonal Antibody is a Rabbit antibody targeting IL-18. Anti-IL-18 Polyclonal Antibody can be used in WB.
Anti-IL-18 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-IL-18 Polyclonal Antibody is a Rabbit antibody targeting IL-18. Anti-IL-18 Polyclonal Antibody can be used in WB. |
| Synonyms | interleukin 18, Il-18, Igif |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 25 μg total protein per Lane of various lysates probed with IL-18 polyclonal antibody, unconjugated (TMAB-00950) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.  |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. |
| Immunogen | Recombinant Protein: human IL-18 |
| Antigen Species | Human |
| Gene Name | IL18 |
| Gene ID | |
| Protein Name | Interleukin-18 |
| Uniprot ID | |
| Biology Area | Hypoxia,Interleukins,Interleukins,Angiogenic growth factors,Response to hypoxia |
| Function | Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. |
| Molecular Weight | Theoretical: 22 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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