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Epristeride

Name: Epristeride
Brand: TargetMol
SKU: T15239
Price: 100 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T15239Cas No. 119169-78-7

Alias SKF105657, ONO-9302

Epristeride (ONO-9302) is an orally active, selective and non-competitive steroidal 5-α-reductase isoform 2 inhibitor that inhibits SR isoform 2.Episteride reduces prostate size and improves symptoms in men with BPH.Episteride induces atrophy and apoptosis of the ventral prostate in rats.

Epristeride

🥰Excellent

Purity: 98.12%

Catalog No. T15239Alias SKF105657, ONO-9302Cas No. 119169-78-7

Pack Size	Price	Availability
1 mg	$100	In Stock
2 mg	$147	In Stock
5 mg	$247	In Stock
10 mg	$396	In Stock
25 mg	$795	In Stock
1 mL x 10 mM (in DMSO)	$272	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.12%

ee:100%

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COA CSFC HNMR LCMS

Product Introduction

Bioactivity

Description	Epristeride (ONO-9302) is an orally active, selective and non-competitive steroidal 5-α-reductase isoform 2 inhibitor that inhibits SR isoform 2.Episteride reduces prostate size and improves symptoms in men with BPH.Episteride induces atrophy and apoptosis of the ventral prostate in rats.
Targets&IC50	SR2:0.7-2 nM (Ki)
In vitro	Epristeride reduces ACP activity and induces cell apoptosis, making it suitable for research related to benign prostatic hyperplasia[1].
Synonyms	SKF105657, ONO-9302

Chemical Properties

Molecular Weight	399.57
Formula	C₂₅H₃₇NO₃
Cas No.	119169-78-7
Smiles	[H][C@@]12CC[C@H](C(=O)NC(C)(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C=C(CC[C@]12C)C(O)=O
Relative Density.	1.13 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (200.22 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5027 mL	12.5135 mL	25.0269 mL	125.1345 mL
5 mM	0.5005 mL	2.5027 mL	5.0054 mL	25.0269 mL
10 mM	0.2503 mL	1.2513 mL	2.5027 mL	12.5135 mL
20 mM	0.1251 mL	0.6257 mL	1.2513 mL	6.2567 mL
50 mM	0.0501 mL	0.2503 mL	0.5005 mL	2.5027 mL
100 mM	0.0250 mL	0.1251 mL	0.2503 mL	1.2513 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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