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Anti-CD226 Antibody-PE (1M594) is a PE-conjugated Rabbit antibody targeting CD226. Anti-CD226 Antibody-PE (1M594) can be used in FCM.
Description | Anti-CD226 Antibody-PE (1M594) is a PE-conjugated Rabbit antibody targeting CD226. Anti-CD226 Antibody-PE (1M594) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1M594 |
Reactivity | Mouse |
Verified Activity | Analysis of CD226 expression on spleen lymphocytes. |
Application | FCM |
Recommended Dose | 10 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD226 / DNAM-1 (rM CD226 / DNAM-1; TMPY-01177; NP_848802.2; Met1-Pro254) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
Research Background | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD226, also known as PTA1 or DNAM-1, is a member of the immunoglobulin superfamily containing 2 Ig-like domains of the V-set. High rate of CD226 (Cluster of Differentiation 226) is found on the surface of natural killer cells, platelets, monocytes and a subset of T cells. CD226 have binding sites with CD112 and CD155 and mediate cellular adhesion to other cells containing its ligands.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
Conjucates | PE |
Others Formats | Unconjugated/APC/FITC |
Antibody Types Available | 4 |
Immunogen | Recombinant Mouse CD226 / DNAM-1 protein (TMPY-01177) |
Antigen Species | Mouse |
Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules, Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Transport | Shipping with blue ice. |
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