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Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody
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Catalog No. TMAC-03328
Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKC beta (Ser661). Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody can be used in WB.
Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody
Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody
😃Good
Catalog No. TMAC-03328
Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKC beta (Ser661). Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $316 | 7-10 days |
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| Description | Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKC beta (Ser661). Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 661 (G-F-S(p)-Y-T) derived from Human PKCB |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 77 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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