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Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody

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Catalog No. TMAC-03328

Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKC beta (Ser661). Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody can be used in WB.

Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody

Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody

😃Good
Catalog No. TMAC-03328
Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKC beta (Ser661). Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2187-10 days
100 μL$3167-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PKC beta (Ser661). Anti-Phospho-PKC beta (Ser661) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundCalcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 661 (G-F-S(p)-Y-T) derived from Human PKCB
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 77 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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