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Anti-MAPK3 Antibody (6G827)

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Catalog No. TMAC-01367

Anti-MAPK3 Antibody (6G827) is a Rabbit antibody targeting MAPK3. Anti-MAPK3 Antibody (6G827) can be used in WB,IP.

Anti-MAPK3 Antibody (6G827)

Anti-MAPK3 Antibody (6G827)

😃Good
Catalog No. TMAC-01367
Anti-MAPK3 Antibody (6G827) is a Rabbit antibody targeting MAPK3. Anti-MAPK3 Antibody (6G827) can be used in WB,IP.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-MAPK3 Antibody (6G827) is a Rabbit antibody targeting MAPK3. Anti-MAPK3 Antibody (6G827) can be used in WB,IP.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, designated extracellular-signal related kinase 1 (ERK 1) and ERK 2, respectively. ERK proteins are regulated by dual phosphorylation at Tyrosine 204 and 187 and Threonine 177 and 160 residues mapping within a characteristic Thr-Glu-Tyr motif. Phosphorylation at both the Threonine 202 and Tyrosine 204 residues of ERK1 and Threonine 185 and Tyrosine 187 residues of ERK2 is required for full enzymatic activation. The structural consequences of dual-phosphorylation in the ERK2 include active site closure, alignment of key catalytic residues that interact with ATP, and remodeling of the activation loop. In response to activation, MAP kinases phosphorylate downstream components on serine and threonine. Upstream MAP kinase regulators include MAP kinase kinase (MEK), MEK kinase and Raf-1. The ERK family has three additional members: ERK 3, ERK 5 and ERK 6.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthesized phosphopeptide: human Erk1/2 around the phosphorylation site of Thr 202 and Tyr204/Thr 185 and Tyr187
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 42/44 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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