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Anti-MAPK3 Antibody (6G827)
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Catalog No. TMAC-01367
Anti-MAPK3 Antibody (6G827) is a Rabbit antibody targeting MAPK3. Anti-MAPK3 Antibody (6G827) can be used in WB,IP.
Anti-MAPK3 Antibody (6G827)
Anti-MAPK3 Antibody (6G827)
😃Good
Catalog No. TMAC-01367
Anti-MAPK3 Antibody (6G827) is a Rabbit antibody targeting MAPK3. Anti-MAPK3 Antibody (6G827) can be used in WB,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-MAPK3 Antibody (6G827) is a Rabbit antibody targeting MAPK3. Anti-MAPK3 Antibody (6G827) can be used in WB,IP. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated through two closely related MAP kinases, p44 and p42, designated extracellular-signal related kinase 1 (ERK 1) and ERK 2, respectively. ERK proteins are regulated by dual phosphorylation at Tyrosine 204 and 187 and Threonine 177 and 160 residues mapping within a characteristic Thr-Glu-Tyr motif. Phosphorylation at both the Threonine 202 and Tyrosine 204 residues of ERK1 and Threonine 185 and Tyrosine 187 residues of ERK2 is required for full enzymatic activation. The structural consequences of dual-phosphorylation in the ERK2 include active site closure, alignment of key catalytic residues that interact with ATP, and remodeling of the activation loop. In response to activation, MAP kinases phosphorylate downstream components on serine and threonine. Upstream MAP kinase regulators include MAP kinase kinase (MEK), MEK kinase and Raf-1. The ERK family has three additional members: ERK 3, ERK 5 and ERK 6. |
| Conjucates | Unconjugated |
| Immunogen | A synthesized phosphopeptide: human Erk1/2 around the phosphorylation site of Thr 202 and Tyr204/Thr 185 and Tyr187 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 42/44 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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