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Anti-CD20 Antibody-PE (8W940)

🥰Excellent
Catalog No. TMAY-01445P

Anti-CD20 Antibody-PE (8W940) is a PE-conjugated Rabbit antibody targeting CD20. Anti-CD20 Antibody-PE (8W940) can be used in FCM.

Anti-CD20 Antibody-PE (8W940)

Anti-CD20 Antibody-PE (8W940)

🥰Excellent
Catalog No. TMAY-01445P
Anti-CD20 Antibody-PE (8W940) is a PE-conjugated Rabbit antibody targeting CD20. Anti-CD20 Antibody-PE (8W940) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-CD20 Antibody-PE (8W940) is a PE-conjugated Rabbit antibody targeting CD20. Anti-CD20 Antibody-PE (8W940) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
Clone
8W940
Reactivity
Human
Verified Activity
Profile of anti-CD20 reactivity on peripheral blood lymphocytes analyzed by flow cytometry.
Application
FCM
Recommended Dose
2 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, Human CD20 Transfected CHO Cells and conjugated with PE under optimum conditions, the unreacted PE was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundCD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20 / MS4A1 is expressed in all stages of B cell development except the first and last. CD20 / MS4A1 is present from pre-pre B cells through memory cells, but not on either pro-B cells or plasma cells. It is a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into plasma cells. CD20 / MS4A1may be involved in the regulation of B-cell activation and proliferation. Defects in CD20 / MS4A1 are the cause of immunodeficiency common variable type 5(CVID5). CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections, and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells are usually in the normal range but can be very low.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
PE
Others Formats
Unconjugated/APC/PerCP/FITC
Antibody Types Available
5
Antigen Details
Immunogen
Human CD20 Transfected CHO Cells
Antigen Species
Human
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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