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Atriopeptin II (rat, mouse)
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Catalog No. TP2547Cas No. 89139-54-8
Atriopeptin II rat, mouse, is an atrial natriuretic peptide that functions as both a diuretic and a natriuretic agent, while also serving as a potent relaxant of vascular smooth muscle [1].
Atriopeptin II (rat, mouse)
😃Good
Catalog No. TP2547Cas No. 89139-54-8
Atriopeptin II rat, mouse, is an atrial natriuretic peptide that functions as both a diuretic and a natriuretic agent, while also serving as a potent relaxant of vascular smooth muscle [1].
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Chemical Properties
| Description | Atriopeptin II rat, mouse, is an atrial natriuretic peptide that functions as both a diuretic and a natriuretic agent, while also serving as a potent relaxant of vascular smooth muscle [1]. |
| In vitro | Atriopeptin II rat, mouse (10 nM, 100 min) exhibits vasodilatory effects in isolated rat thoracic aorta, increases cyclic GMP levels, and activates cyclic GMP kinase [1]. Atriopeptin II rat, mouse (0-100 nM) can stimulate testosterone production, with a half-maximal stimulatory concentration of 2.6 nM [2]. |
| Molecular Weight | 2386.63 |
| Formula | C98H156N34O32S2 |
| Cas No. | 89139-54-8 |
| Smiles | [C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC(=O)[C@@H]2CSSC[C@H](NC([C@@H](NC([C@H](CO)N)=O)CO)=O)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@]([C@H](CC)C)(C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@]([C@H](CC)C)(C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N2)[H])[H])CC(N)=O)=O)CO)=O)C(N[C@@H](CCCNC(=N)N)C(O)=O)=O |
| Sequence | Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg (Disulfide bridge: Cys3-Cys19) |
| Sequence Short | SSCFGGRIDRIGAQSGLGCNSFR (Disulfide bridge: Cys3-Cys19) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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