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Anti-NUMA1 Antibody (6H53)
(Synonyms: SP-H antigen, NuMA protein, NUMA 1, NUMA, Nuclear mitotic apparatus protein 1, Nuclear mitotic apparatus protein, Nuclear matrix protein-22, NMP-22, NMP22) Copy Product Info
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Synonyms: SP-H antigen, NuMA protein, NUMA 1, NUMA, Nuclear mitotic apparatus protein 1, Nuclear mitotic apparatus protein, Nuclear matrix protein-22, NMP-22, NMP22
Catalog No. TMAB-01276 Copy Product Info
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Anti-NUMA1 Antibody (6H53) is a Rabbit antibody targeting NUMA1. Anti-NUMA1 Antibody (6H53) can be used in ELISA, FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-NUMA1 Antibody
(6H53)
(6H53)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $153 | 7-10 days | 7-10 days | |
| 50 μL | $271 | 7-10 days | 7-10 days | |
| 100 μL | $488 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-NUMA1 Antibody (6H53) is a Rabbit antibody targeting NUMA1. Anti-NUMA1 Antibody (6H53) can be used in ELISA, FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | SP-H antigen, NuMA protein, NUMA 1, NUMA, Nuclear mitotic apparatus protein 1, Nuclear mitotic apparatus protein, Nuclear matrix protein-22, NMP-22, NMP22 |
| Ig Type | IgG |
| Clone | 6H53 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:50-200,IF=1:100-500,ELISA=1:5000-20000,Flow-Cyt=1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus matrix. Chromosome. Cytoplasm, cytoskeleton, spindle pole. Note=Resides in the nuclear matrix during interphases. Dissociates from condensing chromosomes during early prophase, and relocates to the spindle poles via dynein/dynamin association, it remain there until the anaphase onset. Before the complete disintegration of the nuclear lamina. As mitosis progresses it reassociates with telophase chromosomes very early during nuclear reformation, before substantial accumulation of lamins on chromosomal surfaces is evident. Isoform Numa-m: Cytoplasm. Note=Mainly clustered at the centrosomal region. Isoform Numa-s: Cytoplasm. Note=Mainly clustered at the centrosomal region. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | Microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignement and the segregation of chromosomes during mitotic cell division.Functions to tether the minus ends of MTs at the spindle poles, which is critical for the establishment and maintenance of the spindle poles |
| Immunogen | KLH conjugated synthetic peptide: human NUMA1 |
| Antigen Species | Human |
| Gene Name | NUMA1 |
| Gene ID | |
| Protein Name | Nuclear mitotic apparatus protein 1 |
| Uniprot ID | |
| Biology Area | Spindle,Markers |
| Function | Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions. |
| Molecular Weight | Theoretical: 238 kDa. Actual: 238 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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